GRN and ATXN7

  • Data Source:
  • BioGRID (two hybrid)

GRN

ATXN7

Description granulin precursor ataxin 7
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Cortical surface area (MOSTest) ( 32665545)
  • Diastolic blood pressure ( 30224653)
  • Estimated glomerular filtration rate ( 31152163)
  • Red cell distribution width ( 32888494)
  • Refractive error ( 32231278)
  • Schizophrenia ( 28991256 25056061 29483656)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Type 2 diabetes ( 30054458)
Interacting Genes 79 interacting genes: ARFGAP1 ATN1 ATXN7 C22orf39 C4orf17 CACNA1A CCDC33 CCNG1 CCNT1 CDK9 CLPP CRCT1 CRKL CRY1 CXCL5 CYSRT1 DLK1 DLX2 DMRT3 ECM1 ELANE FAM131C FAM76B FANCL FRAT1 GFI1B GLRX3 GNE HK3 HOXA1 HSPG2 KRT18 KRT34 KRTAP1-1 KRTAP1-5 KRTAP10-7 KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP13-2 KRTAP15-1 KRTAP26-1 KRTAP5-9 KRTAP6-1 KRTAP6-2 LCE1A LCE1D LCE1E LCE2B LCE2D LCE3C LCE3E LCE4A MEOX2 NLK NUFIP2 OTX1 P4HB PIK3R2 PLLP POT1 POU4F2 PRKAB2 PTPMT1 RAC1 SGTA SLC13A1 SLPI SMAD9 SMCP SPRY2 TAT TGM2 TLE5 TOP3B TSPAN4 UTP23 VASN YY1 59 interacting genes: ACTN1 ACTN2 ACTN4 ADAM33 AGRN CARD10 CEP70 CEP72 COG6 CRIM1 CRX EFEMP1 EFEMP2 FBN1 FN1 GOLGA2 GOLGA3 GPRASP1 GRN ITPRID2 JAG2 KALRN KAT2A LAMB1 LAMB2 LRSAM1 LTBP4 MATN2 MEGF6 MPRIP NELL1 NELL2 NOC2L NUP62 PICK1 PNMA1 PPP1R12C PSMC1 RABEP1 RAD23A RNF31 SIAH1 SNX1 SPRY1 SUMO1 SUMO2 TAF10 THY1 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM54 TRRAP TXNDC11 UBQLN2 USP22 VCP VWF
Entrez ID 2896 6314
HPRD ID 00733 06365
Ensembl ID ENSG00000030582 ENSG00000163635
Uniprot IDs P28799 O15265 Q9UPD8
PDB IDs 1G26 2JYE 2JYT 2JYU 2JYV 6NUG 2KKR
Enriched GO Terms of Interacting Partners?
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