GPR42 and MS4A1

Data Source:
BioGRID (two hybrid)

		GPR42	MS4A1
Description		G protein-coupled receptor 42	membrane spanning 4-domains A1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane	Extracellular Space Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Plasma Membrane Raft Extracellular Exosome
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	Epidermal Growth Factor Receptor Binding Protein Binding Immunoglobulin Binding MHC Class II Protein Complex Binding Identical Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway	Store-operated Calcium Entry Humoral Immune Response Response To Bacterium B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway Protein Tetramerization Calcium Ion Import Into Cytosol
Pathways
Drugs			Rituximab Ibritumomab tiuxetan Tositumomab Ofatumumab Obinutuzumab Technetium Tc-99m nofetumomab merpentan Ocrelizumab
Diseases
GWAS			Recurrent major depressive disorder ( 29317602)
Interacting Genes		104 interacting genes: ADIPOQ ALOX5AP ANKRD46 APOD ATP13A1 ATP4B ATP6V0B ATP6V0C BNIP3 BTN2A2 C1GALT1 CCDC167 CCL4L2 CD300C CD79A CLCA4 CLEC2D COMT CTXN3 CXCL16 CXCL9 DRAM1 EFNA5 EMP1 ERMP1 FAM3C FXYD3 FXYD6 GJB2 GOSR2 GPR37L1 GYPC IER3IP1 IGFBP5 IL1RL1 ITGAM JPH1 KCNA1 KLRG1 LAT LEPROTL1 LHFPL5 LNPEP LTC4S MFSD5 MFSD6 MGAM MS4A1 NDUFB11 NINJ2 NRM NSG1 PAEP PLP1 PLPP1 PMP22 PNLIPRP1 RPRM RTP2 RUSF1 SCD SERINC1 SERP2 SERTM1 SLC30A2 SLC30A3 SLC30A8 SLC35E4 SLC38A1 SLC38A7 SLC39A2 SLC41A1 SLC41A2 SMCO4 SMIM3 STATH STRIT1 STX8 SYNDIG1 SYNGR1 TEX264 TF TM4SF4 TMBIM6 TMEM140 TMEM147 TMEM182 TMEM19 TMEM237 TMEM239 TMEM242 TMEM262 TMEM30B TMEM60 TMEM65 TRARG1 TREX1 TSPO2 YIF1A YIPF1 YIPF2 YIPF4 YIPF6 ZFPL1	41 interacting genes: ACKR2 AQP6 CD40 CERS4 CLEC14A CREB3 CREB3L1 CSNK2A1 CSNK2A2 FAM209A FCRL3 FYN GORAB GPR42 HSD17B11 HSD17B13 IL7R KASH5 LCK LEUTX LMNA LYN MDM2 MFSD14B MMD MTIF3 REEP2 REEP4 RNF19B RNF5 SLC10A1 SLC10A6 SLC18A1 SLC35C2 THAP4 TMEM31 TMEM72 TMEM82 TMPPE TMX2 TSPO2
Entrez ID		2866	931
HPRD ID		16033	00204
Ensembl ID		ENSG00000126251	ENSG00000156738
Uniprot IDs		A0A0K0PUY3 O15529	A0A024R507 P11836
PDB IDs			1S8B 2OSL 3BKY 3PP4 6VJA 6Y90 6Y92 6Y97 6Y9A
Enriched GO Terms of Interacting Partners?
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