LSMEM1 and ZDHHC15

Data Source:
BioGRID (two hybrid)

		LSMEM1	ZDHHC15
Description		leucine rich single-pass membrane protein 1	zinc finger DHHC-type palmitoyltransferase 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Postsynaptic Density Integral Component Of Golgi Membrane Postsynapse
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process		Protein Targeting To Membrane Synaptic Vesicle Maturation Protein Phosphopantetheinylation Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Regulation Of Dendritic Spine Morphogenesis Protein Localization To Postsynapse Protein Localization To Membrane Protein Targeting To Golgi Apparatus Positive Regulation Of Dendrite Development
Pathways
Drugs
Diseases			Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		6 interacting genes: APP CD53 LSMEM2 MAL TMEM80 ZDHHC15	48 interacting genes: ADCYAP1R1 ARL13B BNIP3 C14orf180 CD79A CELA2B CERCAM CLEC10A CLRN1 CREB3L1 CYB5R3 DHRSX ERGIC3 FAM241B GIMAP1 GOLGA7B GPR152 LEMD1 LEPROTL1 LHFPL5 LMNA LSMEM1 MCEMP1 MTIF3 ORMDL1 ORMDL2 PEX16 PLLP PRAF2 PVR RUSF1 SLC10A6 SMIM1 SNORC STX3 TBXA2R TMEFF2 TMEM120B TMEM128 TMEM14C TMEM222 TMEM42 TMEM52B TNFRSF10B TSNARE1 TUFM VAPB YIPF4
Entrez ID		286006	158866
HPRD ID		08258	06758
Ensembl ID		ENSG00000181016	ENSG00000102383
Uniprot IDs		Q8N8F7	B3KY34 Q96MV8
PDB IDs
Enriched GO Terms of Interacting Partners?
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