C19orf54 and PLAC8

Data Source:
BioGRID (two hybrid)

		C19orf54	PLAC8
Description		chromosome 19 open reading frame 54	placenta associated 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Region Azurophil Granule Lumen
	Molecular Function		Chromatin Binding
	Biological Process		Positive Regulation Of Cell Population Proliferation Response To Cold Negative Regulation Of Multicellular Organism Growth Defense Response To Bacterium Negative Regulation Of Apoptotic Process Neutrophil Degranulation Positive Regulation Of Transcription By RNA Polymerase II Brown Fat Cell Differentiation Positive Regulation Of Cold-induced Thermogenesis
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Carotid intima media thickness (mean) ( 31801372)	QRS interval (sulfonylurea treatment interaction) ( 27958378)
Interacting Genes		67 interacting genes: A1CF ABI2 AGXT ANKS1A ARID5A COL8A1 CYSRT1 DTX2 ENKD1 FAM222B FANCL FBLIM1 FNDC3B FOXH1 FRS3 GLIS2 GLYCTK GPS2 HOXC8 HR HSF4 IGFN1 INCA1 KCTD9 KPRP KRTAP23-1 KRTAP26-1 LASP1 LMO3 MISP NEDD9 NOXA1 PATZ1 PITX1 PLAC8 PLSCR3 POGZ PRKAB2 PROP1 PRR35 QRICH1 RBPMS RBPMS2 ROR2 SAXO1 SMARCD1 SNRPC SPAG8 TBX6 TCAP TCF7L2 TEKT5 TFG TLE5 TLX3 TOLLIP TRAF4 TRIP13 TROAP VAC14 VENTX WDR25 WWOX YPEL3 ZC2HC1C ZC3H10 ZMYND19	24 interacting genes: BAG4 C19orf54 COPS5 CYSRT1 FCHO1 KRTAP12-2 KRTAP19-1 KRTAP19-6 LCE1A LCE1C LCE2B LCE5A MEOX2 PLAGL2 PPP3CA RBPMS RHOXF2 TEX37 TRAF1 TRIP13 UBAP2 USP54 VAMP5 WWOX
Entrez ID		284325	51316
HPRD ID		13449	06335
Ensembl ID		ENSG00000188493	ENSG00000145287
Uniprot IDs		Q5BKX5	Q9NZF1 X2BQ60
PDB IDs
Enriched GO Terms of Interacting Partners?
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