CAVIN1 and NKX2-1

Data Source:
BioGRID (pull down)

		CAVIN1	NKX2-1
Description		caveolae associated protein 1	NK2 homeobox 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Plasma Membrane Caveola Protein-containing Complex Intracellular Membrane-bounded Organelle Membrane Raft	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex
	Molecular Function	RNA Binding Protein Binding RRNA Primary Transcript Binding Identical Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Enzyme Binding
	Biological Process	Transcription Initiation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription RRNA Transcription Protein Secretion Positive Regulation Of Cell Motility	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Regulation Of Transcription By RNA Polymerase II Phospholipid Metabolic Process Axon Guidance Brain Development Endoderm Development Locomotory Behavior Response To Hormone Positive Regulation Of Gene Expression Negative Regulation Of Epithelial To Mesenchymal Transition Globus Pallidus Development Hippocampus Development Cerebral Cortex Cell Migration Forebrain Dorsal/ventral Pattern Formation Forebrain Neuron Fate Commitment Cerebral Cortex GABAergic Interneuron Differentiation Pituitary Gland Development Cell Differentiation Lung Development Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Thyroid Gland Development Forebrain Development Developmental Induction Leydig Cell Differentiation Positive Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Rhythmic Process Anatomical Structure Formation Involved In Morphogenesis Oligodendrocyte Differentiation Lung Saccule Development Epithelial Tube Branching Involved In Lung Morphogenesis Club Cell Differentiation Type II Pneumocyte Differentiation
Pathways		RNA Polymerase I Transcription Termination
Drugs
Diseases			Choreoathetosis, hypothyroidism, and neonatal respiratory distress
GWAS			Differentiated thyroid cancer ( 28703219) Height ( 18391950) Menarche (age at onset) ( 23667675 29773799) Papillary thyroid cancer ( 28703219) Thyroid cancer ( 19198613)
Interacting Genes		23 interacting genes: CAVIN3 CDC37 CDCA7L DNTTIP2 DUX4 ERCC6 FBXO28 INO80B KAT5 MRPL45 NKX2-1 SPANXN2 SPANXN3 TNFAIP8L1 TSGA10IP TTC5 TTF1 UBC YAF2 ZCCHC10 ZFP1 ZNF148 ZSCAN21	15 interacting genes: CALR CAVIN1 CREBBP FOXA1 GATA6 HIPK2 MAPK1 NCOA1 NCOA2 NCOA3 PAX8 RARA RELA TDG WWTR1
Entrez ID		284119	7080
HPRD ID		04433	02798
Ensembl ID		ENSG00000177469	ENSG00000136352
Uniprot IDs		Q6NZI2	P43699
PDB IDs
Enriched GO Terms of Interacting Partners?
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