RASSF3 and KYNU

Data Source:
BioGRID (two hybrid)

		RASSF3	KYNU
Description		Ras association domain family member 3	kynureninase
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Microtubule Plasma Membrane	Nucleoplasm Cytoplasm Mitochondrion Cytosol
	Molecular Function	Protein Binding Identical Protein Binding	Pyridoxal Phosphate Binding Kynureninase Activity Protein Homodimerization Activity 3-hydroxykynureninase Activity
	Biological Process	Signal Transduction Regulation Of Apoptotic Process	Tryptophan Catabolic Process Aging NAD Biosynthetic Process Tryptophan Catabolic Process To Kynurenine Tryptophan Catabolic Process To Acetyl-CoA Quinolinate Biosynthetic Process Response To Interferon-gamma 'de Novo' NAD Biosynthetic Process From Tryptophan Response To Vitamin B6 Anthranilate Metabolic Process L-kynurenine Catabolic Process
Pathways			Tryptophan catabolism
Drugs			Pyridoxal phosphate Alanine m-Hydroxyhippuric acid
Diseases
GWAS		Cardiometabolic and hematological traits ( 27668658) Lung adenocarcinoma ( 28604730) Lung function (FEV1/FVC) ( 30804560) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494 27863252) Prostate cancer ( 29892016) Resting heart rate ( 29769521 27798624)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Blood protein levels ( 30072576 29875488 28240269) Empathy quotient ( 29527006) Glomerular filtration rate in chronic kidney disease ( 26420894) Neurological blood protein biomarker levels ( 31320639) Platelet count ( 32888494) Response to SSRI (symptom remission) ( 29160301) Toenail selenium levels ( 25343990)
Interacting Genes		14 interacting genes: APP CBX8 DAXX FAM110A ITPRIP KDM1A KYNU LITAF PARD6B RPRD1B TENT5D TFRC TRIM59 ZNF410	9 interacting genes: CDC42 CT55 CTBP2 FAM86C1P LMO4 MCCD1 MYOZ3 PIP4K2B RASSF3
Entrez ID		283349	8942
HPRD ID		08448	08940
Ensembl ID		ENSG00000153179	ENSG00000115919
Uniprot IDs		Q86WH2	Q16719
PDB IDs			2HZP 3E9K
Enriched GO Terms of Interacting Partners?
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