TMEM80 and ADGRE2

Data Source:
BioGRID (two hybrid)

		TMEM80	ADGRE2
Description		transmembrane protein 80	adhesion G protein-coupled receptor E2
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Ciliary Transition Zone	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Leading Edge Membrane Ruffle Membrane
	Molecular Function	Protein Binding	G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding Chondroitin Sulfate Binding
	Biological Process	Non-motile Cilium Assembly	Inflammatory Response Cell Adhesion Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell Migration Regulation Of Mast Cell Degranulation Granulocyte Chemotaxis
Pathways			Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Plasma androstenedione levels in resected early stage-receptor positive breast cancer ( 28429243)
Interacting Genes		65 interacting genes: ADGRE2 AGTR1 AIG1 AQP1 ARL6IP6 BET1 BIK C11orf24 C14orf180 C3orf52 C5orf46 CCDC167 CD63 CLDN11 CLDN19 CLDN8 CLDND2 CLEC2D CMTM5 CNIH3 COL4A5 CXCR2 CYBC1 DOLK EMD ERMP1 FAM20B FAM3C FKBP8 FXYD3 GPR37L1 IER3IP1 LAT LSMEM1 MALL MRAP2 NKG7 PRB1 PTPN9 PTPRN RPRM SERP2 SLC30A8 SLC66A2 SMAGP SMCO4 STATH STX7 SYNGR1 TLCD1 TMEM100 TMEM107 TMEM109 TMEM120B TMEM128 TMEM14A TMEM243 TMEM65 TNFRSF10C TRARG1 TSPAN1 TSPO2 TVP23B VKORC1L1 WNT4	19 interacting genes: AQP6 BIK CCDC107 CREB3L1 ELOVL4 ELOVL7 FAM209A FCER1G HSD17B13 KIR2DL3 LMNA MARCHF6 MFSD5 MMGT1 MTERF3 SAR1A SLC7A14 TLCD4 TMEM80
Entrez ID		283232	30817
HPRD ID		14143	07308
Ensembl ID		ENSG00000177042	ENSG00000127507
Uniprot IDs		A0A0A0MTU4 B7Z7W9 Q96HE8	A0JNV7 Q9UHX3
PDB IDs			2BO2 2BOU 2BOX
Enriched GO Terms of Interacting Partners?
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