IFNL3 and IL10RB

Data Source:
HPRD (in vivo)

		IFNL3	IL10RB
Description		interferon lambda 3	interleukin 10 receptor subunit beta
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Membrane Interleukin-28 Receptor Complex
	Molecular Function	Signaling Receptor Binding Cytokine Activity	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Signaling Receptor Activity
	Biological Process	Receptor Signaling Pathway Via JAK-STAT Cytokine-mediated Signaling Pathway Negative Regulation Of Viral Genome Replication Innate Immune Response Positive Regulation Of Immune Response Defense Response To Virus	Inflammatory Response Immune Response Signal Transduction Cytokine-mediated Signaling Pathway Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Defense Response To Virus
Pathways		Interleukin-20 family signaling	Other interleukin signaling Interleukin-10 signaling Interleukin-20 family signaling
Drugs
Diseases
GWAS		Hepatitis C (spontaneous viral clearance) ( 30593799) Mucinous ovarian carcinoma ( 26075790)	Blood protein levels ( 30072576) Crohn's disease ( 23128233) Multiple sclerosis ( 31604244) Narcolepsy ( 24204295 23459209)
Interacting Genes		1 interacting genes: IL10RB	7 interacting genes: IFNL2 IFNL3 IL10 IL10RA IL22 UCN2 UCN3
Entrez ID		282617	3588
HPRD ID		09587	00473
Ensembl ID		ENSG00000197110	ENSG00000243646
Uniprot IDs		A0A0C4DGW8 Q8IZI9	Q08334
PDB IDs		3HHC 5T5W	3LQM 5T5W
Enriched GO Terms of Interacting Partners?
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