GOLGA4 and ARL3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GOLGA4	ARL3
Description		golgin A4	ADP ribosylation factor like GTPase 3
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Extracellular Exosome	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Spindle Microtubule Cytoplasmic Microtubule Cilium Microtubule Cytoskeleton Midbody Photoreceptor Connecting Cilium Extracellular Exosome
	Molecular Function	Protein Binding Small GTPase Binding GTPase Binding	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding GDP Binding GTPase Activating Protein Binding
	Biological Process	Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Axon Extension Golgi Vesicle Transport	Mitotic Cytokinesis Kidney Development Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Smoothened Signaling Pathway Small GTPase Mediated Signal Transduction Intraciliary Transport Photoreceptor Cell Development Cilium Assembly Protein Localization To Cilium Protein Localization To Ciliary Membrane
Pathways		Retrograde transport at the Trans-Golgi-Network Signaling by membrane-tethered fusions of PDGFRA or PDGFRB	Trafficking of myristoylated proteins to the cilium
Drugs			2-(N-morpholino)ethanesulfonic acid Guanosine-5'-Diphosphate
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Pulse pressure ( 30578418) Subjective response to lithium treatment ( 26503763)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 30487518) Mean arterial pressure ( 30487518) Mean arterial pressure (long-term average) ( 28348047) Prostate cancer ( 23535732) Pulse pressure ( 30487518) Refractive error ( 32231278) Schizophrenia ( 28991256 25056061 27922604) Systolic blood pressure ( 30487518) Systolic blood pressure (long-term average) ( 28348047) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		8 interacting genes: APP ARL1 ARL3 MACF1 RAB6A SERPINB5 TNIK TRAF3IP1	11 interacting genes: ARL2BP GOLGA4 LRIF1 PDE6D RP2 TBL1X TLE1 TP53 TUBA1A UBR1 UNC119
Entrez ID		2803	403
HPRD ID		03941	05260
Ensembl ID		ENSG00000144674	ENSG00000138175
Uniprot IDs		Q13439 Q49A56	P36405
PDB IDs		1R4A 1UPT
Enriched GO Terms of Interacting Partners?
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