GNL1 and KRT6A

Data Source:
BioGRID (affinity chromatography technology)

		GNL1	KRT6A
Description		G protein nucleolar 1 (putative)	keratin 6A
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome
	Molecular Function	GTPase Activity Structural Molecule Activity GTP Binding	Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	T Cell Mediated Immunity Cellular Response To DNA Damage Stimulus Signal Transduction	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Cell Differentiation Keratinization Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cornification Negative Regulation Of Entry Of Bacterium Into Host Cell
Pathways			Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases			Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Lung cancer ( 28604730) Major depressive disorder ( 27479909) Neuroticism ( 29255261) Rosacea symptom severity ( 29771307) Squamous cell lung carcinoma ( 28604730)	Cutaneous squamous cell carcinoma ( 32041948)
Interacting Genes		4 interacting genes: GDI1 PTP4A1 SIRPA ZNF212	38 interacting genes: BEX2 CCDC85B DSP GEM GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT16 KRT17 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 LMNA MTUS2 NCALD NUP62 SGTA SMARCB1 TCHP TFIP11 TRIM23 TRIM54 TSGA10 TXLNB UBQLN2 WASHC3
Entrez ID		2794	3853
HPRD ID		00879	01011
Ensembl ID		ENSG00000204590	ENSG00000205420
Uniprot IDs		A0A024RCR2 B4DYK6 P36915	A0A0S2Z428 P02538
PDB IDs			5KI0
Enriched GO Terms of Interacting Partners?
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