PGAP2 and GJB5

Data Source:
BioGRID (two hybrid)

		PGAP2	GJB5
Description		post-GPI attachment to proteins 2	gap junction protein beta 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane	Connexin Complex Integral Component Of Membrane
	Molecular Function	Protein Binding	Gap Junction Channel Activity Protein Binding
	Biological Process	GPI Anchor Biosynthetic Process	Cell-cell Signaling Epidermis Development Transmembrane Transport Trophoblast Giant Cell Differentiation Labyrinthine Layer Morphogenesis Epididymis Development
Pathways			Gap junction assembly
Drugs
Diseases
GWAS		Malaria ( 31844061)	Narcolepsy ( 23459209) Sleep duration (short sleep) ( 30846698) Triglyceride levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		31 interacting genes: AMIGO1 ARL13B BIK CD79A CGRRF1 CISD2 CLDN7 CLSTN3 COMT CPLX4 CREB3L1 CYSRT1 ERGIC3 F11R FAM209A FNDC9 GJA5 GJA8 GJB5 GPR152 GPX8 KASH5 KRTAP10-3 KRTAP10-9 LRRC4C PDZK1IP1 SSMEM1 STX1A TMEM52B TMEM9 TMPRSS2	44 interacting genes: APOL2 APOL3 AQP1 C1GALT1 C4orf3 COMT CTXN3 CYB5B ERG28 FAM3C GSK3B IGFBP5 JAGN1 LMNA LPAR3 LRP10 MED1 MIP MS4A13 MYL2 NAPB PCGF2 PGAP2 PLPP4 PLPP6 PNLIPRP1 RPRM RTP2 SEC22A SEC22B SERP1 SLC30A2 SLC38A7 SLC41A1 SLC41A2 SMIM1 TM4SF4 TMEM128 TMEM60 TMEM86A TMEM97 TRIM2 TSPO2 VSTM1
Entrez ID		27315	2709
HPRD ID		17016	06840
Ensembl ID		ENSG00000148985	ENSG00000189280
Uniprot IDs		A0A024RCC6 A0A024RCD5 A0A0A0MS75 A0A0S2Z568 A8MYS5 B7Z2X5 H0YDQ4 Q9UHJ9	A0A654IE64 O95377
PDB IDs
Enriched GO Terms of Interacting Partners?
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