LSM1 and NARS1

Data Source:
HPRD (two hybrid)

		LSM1	NARS1
Description		LSM1 homolog, mRNA degradation associated	asparaginyl-tRNA synthetase 1
Image		No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding	Nucleic Acid Binding Asparagine-tRNA Ligase Activity Protein Binding ATP Binding CCR3 Chemokine Receptor Binding Protein Dimerization Activity
	Biological Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Exonucleolytic Catabolism Of Deadenylated MRNA Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process	TRNA Aminoacylation For Protein Translation Asparaginyl-tRNA Aminoacylation Cell Migration
Pathways		mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease	Cytosolic tRNA aminoacylation
Drugs			Asparagine
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)
Interacting Genes		32 interacting genes: AGR2 AGR3 BEX5 CLIC1 DAPL1 EXOSC6 EXOSC8 GLUD1 GRHPR GSTA4 HSP90AA1 LSM2 LSM3 LSM5 LSM6 LSM7 MCCD1 MPDU1 N4BP1 NARS1 NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TCL1B TFCP2 TMEM214 UPF2 UXT VPS11	4 interacting genes: ATXN1 HSPB2 LSM1 SUMO2
Entrez ID		27257	4677
HPRD ID		06281	00154
Ensembl ID		ENSG00000175324	ENSG00000134440
Uniprot IDs		A0A0S2Z590 O15116	O43776
PDB IDs			4ZYA 5XIX
Enriched GO Terms of Interacting Partners?
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