ARFIP1 and DESI2

Data Source:
BioGRID (two hybrid)

		ARFIP1	DESI2
Description		ADP ribosylation factor interacting protein 1	desumoylating isopeptidase 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol Trans-Golgi Network Membrane	Cytoplasm
	Molecular Function	Protein Binding Phospholipid Binding Protein Domain Specific Binding Phosphatidylinositol-4-phosphate Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Lys63-specific Deubiquitinase Activity Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity
	Biological Process	Intracellular Protein Transport Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Protein Secretion Negative Regulation Of Retrograde Transport, Endosome To Golgi	Protein Deubiquitination Protein Phosphopantetheinylation Protein K63-linked Deubiquitination Protein Modification By Small Protein Removal Protein K48-linked Deubiquitination
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean platelet volume ( 32888494) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		19 interacting genes: AFF1 ARF1 ARF3 ARF5 ARFIP2 BSND CMTM5 DESI2 KRT27 KRT33B MAGEA6 RPRM SCAMP1 SFT2D1 SLC2A4 SMIM5 SMPD2 SYNGR3 TNFRSF10D	11 interacting genes: ARFIP1 BNIP2 COQ8A MYG1 NFU1 PBX3 PLIN2 SEMA3G SH3GLB1 SPART THAP7
Entrez ID		27236	51029
HPRD ID		09331	15153
Ensembl ID		ENSG00000164144	ENSG00000121644
Uniprot IDs		B4E273 B7ZA10 P53367 Q8N8M9	A0A024R5P6 A0A024R5P9 Q9BSY9
PDB IDs
Enriched GO Terms of Interacting Partners?
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