SLC39A1 and KCNAB1

Data Source:
HPRD (two hybrid)

		SLC39A1	KCNAB1
Description		solute carrier family 39 member 1	potassium voltage-gated channel subfamily A member regulatory beta subunit 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane	Cytosol Plasma Membrane Voltage-gated Potassium Channel Complex Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Dendrite Cytoplasm Potassium Channel Complex Perikaryon Juxtaparanode Region Of Axon Proximal Dendrite
	Molecular Function	Signaling Receptor Binding Zinc Ion Transmembrane Transporter Activity Protein Binding Inorganic Cation Transmembrane Transporter Activity	Aldo-keto Reductase (NADP) Activity Voltage-gated Potassium Channel Activity Potassium Channel Regulator Activity Protein Domain Specific Binding Ion Channel Binding NADPH Binding
	Biological Process	In Utero Embryonic Development Cation Transport Embryonic Cranial Skeleton Morphogenesis Limb Development Zinc Ion Transmembrane Transport	Potassium Ion Transport Brain Development Heart Development Skeletal Muscle Tissue Development Myoblast Differentiation Diaphragm Development Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Voltage-gated Potassium Channel Activity
Pathways		Zinc influx into cells by the SLC39 gene family	Voltage gated Potassium channels
Drugs			Enflurane Promethazine Miconazole
Diseases
GWAS		Age at first birth ( 27798627) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Empathy quotient ( 29527006) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Lentiform nucleus volume ( 22903471) Raw vegetable consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Age-related nuclear cataracts ( 24951543) Aging traits ( 17903295) Coronary artery disease ( 26708285) Focal epilepsy (with hippocampal sclerosis) ( 30531953) Offspring birth weight ( 31043758)
Interacting Genes		16 interacting genes: CERS2 COMT CXCL16 CXCL9 CYB561 HTR2C HTR4 KCNAB1 KCNAB2 NOTCH3 PLEKHM2 PRKCZ SHB SLC39A2 TRARG1 YIPF6	9 interacting genes: APP DLG1 FBXO7 KCNA2 NEDD4 NEDD4L SLC39A1 SLC39A2 SRPK1
Entrez ID		27173	7881
HPRD ID		11984	03089
Ensembl ID		ENSG00000143570	ENSG00000169282
Uniprot IDs		A0A0A0MTL8 Q9NY26	B7Z435 B7Z8E5 F8W6W4 Q14722 Q5MJQ3
PDB IDs
Enriched GO Terms of Interacting Partners?
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