TJP3 and GJC1

Data Source:
HPRD (two hybrid)

		TJP3	GJC1
Description		tight junction protein 3	gap junction protein gamma 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Plasma Membrane Bicellular Tight Junction Cell Junction	Endoplasmic Reticulum Membrane Plasma Membrane Gap Junction Connexin Complex Intercalated Disc Integral Component Of Membrane Synapse
	Molecular Function	Protein Binding Cell Adhesion Molecule Binding	Ion Channel Activity Gap Junction Channel Activity Protein Binding Gap Junction Channel Activity Involved In SA Node Cell-atrial Cardiac Muscle Cell Electrical Coupling Gap Junction Channel Activity Involved In AV Node Cell-bundle Of His Cell Electrical Coupling
	Biological Process	Maintenance Of Blood-brain Barrier Cell-cell Junction Organization Establishment Of Endothelial Intestinal Barrier Cell-cell Adhesion Protein Localization To Cell-cell Junction Positive Regulation Of Blood-brain Barrier Permeability	Vasculogenesis Muscle Contraction Cell-cell Junction Assembly Cell-cell Signaling Chemical Synaptic Transmission Visual Perception Gap Junction Assembly Ion Transmembrane Transport Cell Development Cardiac Muscle Tissue Development Atrial Cardiac Muscle Cell Action Potential SA Node Cell To Atrial Cardiac Muscle Cell Communication By Electrical Coupling AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling
Pathways			Electric Transmission Across Gap Junctions Gap junction assembly
Drugs
Diseases
GWAS		Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) ( 31372216)
Interacting Genes		5 interacting genes: CLDN1 FASLG GJC1 PATJ TJP1	8 interacting genes: APOL3 CNST MEOX2 SLC66A1 TJP1 TJP3 TMEM86A UBQLN4
Entrez ID		27134	10052
HPRD ID		18194	08819
Ensembl ID		ENSG00000105289	ENSG00000182963
Uniprot IDs		O95049	A0A654IDC0 P36383
PDB IDs		3KFV	3SHW
Enriched GO Terms of Interacting Partners?
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