UQCRQ and POLR2M

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UQCRQ	POLR2M
Description		ubiquinol-cytochrome c reductase complex III subunit VII	RNA polymerase II subunit M
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Integral Component Of Membrane	Intracellular Anatomical Structure Nuclear Envelope RNA Polymerase II, Core Complex RNA Polymerase II, Holoenzyme Neuronal Cell Body
	Molecular Function	Ubiquinol-cytochrome-c Reductase Activity	DNA-directed 5'-3' RNA Polymerase Activity
	Biological Process	Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Subthalamus Development Pons Development Cerebellar Purkinje Cell Layer Development Hippocampus Development Thalamus Development Hypothalamus Development Pyramidal Neuron Development Midbrain Development	RNA Biosynthetic Process Intracellular Signal Transduction Maintenance Of ER Location
Pathways		Respiratory electron transport
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Asthma ( 31619474)	Body mass index ( 28552196) Seasonality ( 25562672)
Interacting Genes		4 interacting genes: ERCC6 ERCC8 OPTN POLR2M	22 interacting genes: AHSP ANKHD1 APOD CEBPG CEP126 DAPK1 DGKZ HIGD1B LRRK1 LRRK2 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410
Entrez ID		27089	81488
HPRD ID		17941	07575
Ensembl ID		ENSG00000164405	ENSG00000255529
Uniprot IDs		O14949	P0CAP1 P0CAP2 Q6EEV4
PDB IDs		5XTE 5XTH 5XTI	2KXS 6DRD
Enriched GO Terms of Interacting Partners?
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