SND1 and MYBL2

Data Source:
HPRD (in vitro)

		SND1	MYBL2
Description		staphylococcal nuclease and tudor domain containing 1	MYB proto-oncogene like 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane RISC Complex Melanosome Extracellular Exosome Dense Body	Nucleus Nucleoplasm Myb Complex
	Molecular Function	Transcription Coregulator Activity RNA Binding Nuclease Activity Endonuclease Activity Endoribonuclease Activity Protein Binding Cadherin Binding RISC Complex Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Osteoblast Differentiation Regulation Of Transcription, DNA-templated RNA Catabolic Process Regulation Of Cell Cycle Process MiRNA Catabolic Process Viral Process Gene Silencing By RNA RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Mitotic Cell Cycle Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Cycle Mitotic Spindle Assembly Cellular Response To Leukemia Inhibitory Factor
Pathways		Signaling by BRAF and RAF fusions	Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 Polo-like kinase mediated events TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
Drugs
Diseases
GWAS		Birth weight ( 31043758) Brain morphology (MOSTest) ( 32665545) Cadmium levels ( 26025379) Coffee consumption ( 31046077) Estimated glomerular filtration rate ( 31152163) Fruit consumption ( 32066663) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Hemoglobin A1c levels ( 29403010) Number of sexual partners ( 30643258) Offspring birth weight ( 31043758) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 32499647 23532257)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		23 interacting genes: APP CREBBP CSNK2A1 ESR1 GTF2E1 GTF2E2 LZTR1 MAK MYB MYBL2 PIM1 POLR2A PRPF8 PTGER4 RBPJ RNU1-1 RNU2-1 RNU4-1 RNU5A-1 RNU6-1 STAT6 SUMO2 UBE2I	31 interacting genes: CCNA1 CCNA2 CCND1 CCNE1 CCNF CDC34 CDK2 CDK9 CREBBP CXCR4 E2F1 E2F3 EP300 LIN52 LIN9 LZTR1 MAP1LC3B MAPK6 NCOR1 NCOR2 PARP1 RBBP4 RBL1 SKP2 SND1 TRIM15 TTF2 UBB UBE2D4 ZBTB9 ZNF622
Entrez ID		27044	4605
HPRD ID		03714	03247
Ensembl ID		ENSG00000197157	ENSG00000101057
Uniprot IDs		A0A140VK49 Q7KZF4	P10244
PDB IDs		2E6N 2HQE 2HQX 2O4X 3BDL 3OMC 3OMG 4QMG 5M9O	6C48
Enriched GO Terms of Interacting Partners?
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