USP21 and WDR47

Data Source:
BioGRID (two hybrid)

		USP21	WDR47
Description		ubiquitin specific peptidase 21	WD repeat domain 47
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane	Cytoplasm Microtubule
	Molecular Function	Transcription Coactivator Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity NEDD8-specific Protease Activity Metal Ion Binding	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Histone Deubiquitination Protein Deubiquitination Protein Phosphopantetheinylation Neuron Projection Development Positive Regulation Of Transcription, DNA-templated	Multicellular Organism Development
Pathways		TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway Ub-specific processing proteases
Drugs
Diseases
GWAS
Interacting Genes		59 interacting genes: ADAMTSL4 ATXN3 AURKA BAP1 BRCA2 CBL CBLC CPSF6 DTX3 EFEMP2 ESPL1 EXOSC10 FOXM1 H2AC18 HOXC10 ISG15 JOSD1 KCTD9 KRT40 LRSAM1 MAPK3 MPP1 NANOG OTUB1 OTUB2 PCGF6 RBCK1 RNF144A RNF185 SENP3 SENP8 SLF1 STAMBP SYNE1 TP53 TRAF6 TRIM23 TRIM5 TRIM54 TRIM63 TRIM8 TRIM9 UBC UBE2S UCHL1 UCHL3 USP14 USP15 USP2 USP20 USP28 USP33 USP4 USP51 USP7 USP8 WDR47 YOD1 ZNF350	5 interacting genes: CHFR FAM107A TCEA2 TCL1A USP21
Entrez ID		27005	22911
HPRD ID		05291	15670
Ensembl ID		ENSG00000143258	ENSG00000085433
Uniprot IDs		Q9UK80	O94967
PDB IDs		2Y5B 3I3T 3MTN
Enriched GO Terms of Interacting Partners?
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