RGS17 and LCE3C

Data Source:
BioGRID (two hybrid)

		RGS17	LCE3C
Description		regulator of G protein signaling 17	late cornified envelope 3C
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Neuron Projection Synapse
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding	Protein Binding
	Biological Process	Response To Amphetamine G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity	Keratinization Killing Of Cells Of Other Organism Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events	Formation of the cornified envelope
Drugs
Diseases
GWAS		Adult body size ( 32376654) Alcohol dependence ( 26365420) Apolipoprotein A1 levels ( 32203549) Bacterial meningitis ( 31092817) Body mass index ( 28892062) Cuneus cortex volume ( 31530798) Diastolic blood pressure ( 30224653) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 29083408) Lipoprotein (a) levels ( 26377243) Morning person ( 30696823) Pneumococcal meningitis ( 31092817) Prostate cancer ( 23535732) Triglyceride levels ( 32203549)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		43 interacting genes: ADRB2 AQP1 BOLA2 BOLA2B CHRD CRCT1 CREB5 DHX37 GNAI1 GNAI3 HOXA1 HSD3B7 KRTAP4-11 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 LCE1A LCE1B LCE1D LCE1E LCE2A LCE2B LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A NUFIP2 OSTM1 OTX1 PTGER3 RABEP1 RBBP8 RPL10A SLC39A7 SMCP STUB1 TBC1D16 VASN	55 interacting genes: ADAMTSL4 ALPP CHIC2 CYP21A2 CYSRT1 EFEMP2 GRN HOXA1 KPRP KRT31 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP3-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 LCE1B MDFI NBPF19 NOTCH2NLA PCSK5 PLSCR1 RGS17 RGS20 SPRY1 SPRY2 TRIM42 TSPAN4 ZNF655
Entrez ID		26575	353144
HPRD ID		06223	17262
Ensembl ID		ENSG00000091844	ENSG00000244057
Uniprot IDs		Q9UGC6	Q5T5A8
PDB IDs		1ZV4 6AM3
Enriched GO Terms of Interacting Partners?
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