IL36RN and SSBP4

Data Source:
HPRD (two hybrid)

		IL36RN	SSBP4
Description		interleukin 36 receptor antagonist	single stranded DNA binding protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Nucleus
	Molecular Function	Cytokine Activity Interleukin-1 Receptor Binding Interleukin-1 Receptor Antagonist Activity Protein Binding	Single-stranded DNA Binding Protein Binding
	Biological Process	Negative Regulation Of Cytokine-mediated Signaling Pathway Inflammatory Response To Antigenic Stimulus Inflammatory Response Cytokine-mediated Signaling Pathway Antifungal Humoral Response Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Innate Immune Response Cellular Response To Lipopolysaccharide	Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Interleukin-36 pathway
Drugs
Diseases
GWAS		Menstruation quality of life impact (dysmenorrhea) ( 29855537) Pain medicine use during menstruation ( 29855537) Stroke ( 26089329)	Alzheimer's disease (late onset) ( 30820047) Basophil count ( 32888494) Breast cancer ( 23535729) Intake of total sugars ( 31005972) Monocyte count ( 27863252) Systemic lupus erythematosus ( 33536424 28714469)
Interacting Genes		18 interacting genes: AGR2 AP3M1 CNOT4 CRACR2B DDIT4L HPCA INCA1 IRAK4 MCM6 REL SH2B2 SKIL SSBP2 SSBP3 SSBP4 UBL4B ZKSCAN4 ZNF512B	8 interacting genes: IL36RN LDB1 LDB2 MYO15B PIK3R3 PIN1 SPG21 TFAP2B
Entrez ID		26525	170463
HPRD ID		16112	09579
Ensembl ID		ENSG00000136695	ENSG00000130511
Uniprot IDs		A0A024R518 Q9UBH0	Q9BWG4
PDB IDs		4P0J 4P0K 4P0L
Enriched GO Terms of Interacting Partners?
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