HSPB8 and C2CD6

Data Source:
BioGRID (two hybrid)

		HSPB8	C2CD6
Description		heat shock protein family B (small) member 8	C2 calcium dependent domain containing 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body Chaperone Complex
	Molecular Function	Protein Kinase Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Protein Phosphorylation Cellular Response To Unfolded Protein Regulation Of Cellular Response To Heat Positive Regulation Of Aggrephagy
Pathways		HSF1-dependent transactivation
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy Distal hereditary motor neuropathies (dHMN)
GWAS		Metabolite levels ( 23823483) PR interval in Tripanosoma cruzi seropositivity ( 24324551)
Interacting Genes		22 interacting genes: ATXN7L2 BAG3 C2CD6 CRYAB CSNK2A1 DUSP12 FAM214B HSPB1 HSPB2 HSPB3 HSPB6 HSPB7 MAPK3 MISP MLF2 PRKCA QRICH1 RPIA SLC16A5 SNCA SOCS7 TRAPPC6A	62 interacting genes: ACOT11 ACTN3 ANKK1 AP2B1 BBS4 BHLHB9 BRCA1 CARD9 CCDC172 CCDC57 CCDC85B CDR2 CHCHD3 CNOT11 CT55 DISC1 DNAJA3 FAM217B FHL2 GOLGA2 GRAMD4 HAP1 HSF2BP HSPB8 IKZF3 JRK KIFC3 KRT13 KRT15 KRT31 KRT40 KRT75 LHX1 LHX3 LZTS2 MCM6 MCRS1 MEAF6 MEOX1 MIPOL1 MTUS2 NR5A1 NUTM1 PAX6 PIBF1 RNF8 SPATA2 TACC3 TCP10L TEX11 TFIP11 TLE5 TRAF1 TRAF2 TRIM23 TRIM54 TSSK3 VAC14 VIM VPS52 ZNF474 ZNRD2
Entrez ID		26353	151254
HPRD ID		06420	08687
Ensembl ID		ENSG00000152137	ENSG00000155754
Uniprot IDs		Q9UJY1	A0A140VJE2 Q53TS8
PDB IDs
Enriched GO Terms of Interacting Partners?
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