CLEC4E and FAM3C

Data Source:
BioGRID (two hybrid)

		CLEC4E	FAM3C
Description		C-type lectin domain family 4 member E	FAM3 metabolism regulating signaling molecule C
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GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space Golgi Apparatus Platelet Dense Granule Lumen Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Carbohydrate Binding Pattern Recognition Receptor Activity	Cytokine Activity Protein Binding
	Biological Process	Pattern Recognition Receptor Signaling Pathway Stimulatory C-type Lectin Receptor Signaling Pathway Innate Immune Response	Platelet Degranulation Signal Transduction Multicellular Organism Development Biological_process Negative Regulation Of Gluconeogenesis
Pathways		Dectin-2 family Dectin-2 family	Platelet degranulation
Drugs		Cholesterol
Diseases
GWAS		Takayasu arteritis ( 25604533)	Biomedical quantitative traits ( 19396169) Bone mineral density (paediatric, lower limb) ( 24945404) Bone mineral density (paediatric, skull) ( 24945404) Bone mineral density (paediatric, total body less head) ( 24945404) Bone mineral density (paediatric, upper limb) ( 24945404) Calcaneus stiffness index ( 30779856) Forearm bone mineral density ( 26367794) Hand grip strength ( 27325353) Heel bone mineral density ( 30598549 28869591) Lung adenocarcinoma ( 28604730) Pediatric bone mineral content (radius) ( 26041818) Phenylephrine infusion rate during anesthesia ( 31455332) Total body bone mineral density ( 30172743) Ulna and radius bone mineral density ( 30172743)
Interacting Genes		4 interacting genes: CXCL9 FAM3C FCER1G NKG7	48 interacting genes: AHNAK2 BIK BNIP2 CLEC17A CLEC2D CLEC4E CREB3 CREB3L1 CXADR CYB5R3 ELOVL4 ERGIC3 EVI2B FAM209A FCGR1A FCGRT FFAR2 FKBP7 GGT6 GJB5 GPR42 GPX8 HHLA2 KCNA2 KIR2DL3 LMNA LRRC25 MFF PDZK1IP1 RELL2 RMDN3 RNASEH1 SAR1A SCN3B SLC10A6 SLC16A2 SLC18A1 SLC35C2 SPINT1 SSMEM1 STX1A TEX29 TMEM248 TMEM45B TMEM71 TMEM80 TMPRSS2 TMX2
Entrez ID		26253	10447
HPRD ID		13075	12270
Ensembl ID		ENSG00000166523	ENSG00000196937
Uniprot IDs		F5H5X7 Q9ULY5	Q92520
PDB IDs		3WH2 3WH3	5LC2
Enriched GO Terms of Interacting Partners?
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