LCE2B and KRTAP4-5

Data Source:
BioGRID (two hybrid)

		LCE2B	KRTAP4-5
Description		late cornified envelope 2B	keratin associated protein 4-5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component	Cytosol Keratin Filament
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Epidermis Development Keratinization	Aging Keratinization Hair Cycle
Pathways		Formation of the cornified envelope	Keratinization
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		65 interacting genes: ADAMTSL4 CRCT1 CYSRT1 DHRS1 GRN GUCD1 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-1 KRTAP3-3 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-2 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2C LCE2D LCE3A LCE3D LCE4A LCE5A MDFI NBPF19 NECTIN2 NOTCH2NLA NR4A3 OTX1 PLA2G10 PLAC8 PLSCR3 PLSCR4 RGS17 RGS20 RNF4 SPRED2 SPRY3 TGFB1 TRIM42 TSPAN4	62 interacting genes: AXIN2 BAG4 CRCT1 CREB5 CYSRT1 FAM76B FBXO34 GATA1 GLRX3 HOXA1 KPRP KRTAP1-1 KRTAP1-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP12-1 KRTAP13-2 KRTAP4-2 KRTAP4-4 KRTAP5-2 KRTAP5-9 KRTAP6-1 KRTAP9-3 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NOTCH2NLA NUFIP2 OTX1 PEAR1 POTEB3 POU4F2 PRKAB2 RORB SH3GLB2 SHFL SLC4A7 SMCP TRIM42 TSPAN4 YY1 ZNF552 ZNF774 ZNF835 ZNF837
Entrez ID		26239	85289
HPRD ID		17260	13946
Ensembl ID		ENSG00000159455	ENSG00000198271
Uniprot IDs		O14633	Q9BYR2
PDB IDs
Enriched GO Terms of Interacting Partners?
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