STAP1 and GRIPAP1

Data Source:
BioGRID (two hybrid)

		STAP1	GRIPAP1
Description		signal transducing adaptor family member 1	GRIP1 associated protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Protein-containing Complex Intracellular Membrane-bounded Organelle	Nucleoplasm Cytosol Axon Dendrite Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Blood Microparticle Postsynaptic Recycling Endosome Glutamatergic Synapse Extrinsic Component Of Postsynaptic Early Endosome Membrane
	Molecular Function	Phosphotyrosine Residue Binding Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Macrophage Colony-stimulating Factor Receptor Binding Protein Binding Phospholipid Binding Protein Kinase Binding Signaling Adaptor Activity	Molecular_function Protein Binding Identical Protein Binding
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Gene Expression Negative Regulation Of Macrophage Chemotaxis Negative Regulation Of Phosphorylation Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Phagocytosis, Engulfment Cellular Response To Lipopolysaccharide Negative Regulation Of Ruffle Assembly Negative Regulation Of Macrophage Colony-stimulating Factor Signaling Pathway Positive Regulation Of Microglial Cell Activation Positive Regulation Of Non-membrane Spanning Protein Tyrosine Kinase Activity Negative Regulation Of Microglial Cell Migration Positive Regulation Of Microglial Cell Mediated Cytotoxicity Positive Regulation Of Actin Cytoskeleton Reorganization	Biological_process Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Regulation Of Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Regulation Of Recycling Endosome Localization Within Postsynapse Regulation Of Modification Of Synaptic Structure
Pathways
Drugs
Diseases
GWAS		Regular attendance at a pub or social club ( 29970889)	Eosinophil percentage of white cells ( 32888494)
Interacting Genes		14 interacting genes: AR EGFR ERBB2 ERBB3 ERBB4 GAB1 GRIPAP1 KIT MET PTK2B RETREG3 SH3KBP1 TEC URI1	69 interacting genes: AARD ANKRD11 ARL15 ATG5 BYSL CASP3 CBX8 CCDC103 CCDC185 CCDC187 CCNH CCNT1 CDC37 CEP57L1 CFAP53 CWF19L2 DAXX DISC1 DUSP26 EHHADH ELOA ENKD1 FAM161A FAM50B FAM90A1 GAS8 GRIA1 GRIP1 GRM7 HDAC4 HSPB1 ING4 ING5 LNX1 MAP3K1 MEOX2 MFAP1 MLLT6 NUAK2 PIBF1 PKP2 PPP1R18 PRPF18 PSMB1 RAB4A RCOR3 SMAD2 SMARCE1 SMURF1 SNAPC5 SNW1 SPP1 STAP1 TBC1D30 TCEA2 TCP10L TEPSIN TES TRAF2 TSGA10IP TSHZ2 TSNAX TTC23 USP2 ZMAT2 ZNF219 ZNF250 ZNF35 ZNF835
Entrez ID		26228	56850
HPRD ID		16053	02325
Ensembl ID		ENSG00000035720	ENSG00000068400
Uniprot IDs		A0A024RD91 Q9ULZ2	Q4V328
PDB IDs		1X1F 3MAZ
Enriched GO Terms of Interacting Partners?
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