GIGYF2 and CAB39

Data Source:
BioGRID (biochemical)

		GIGYF2	CAB39
Description		GRB10 interacting GYF protein 2	calcium binding protein 39
Image
GO Annotations	Cellular Component	Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoplasmic Stress Granule Membrane Protein-containing Complex Perikaryon Proximal Dendrite	Extracellular Region Cytosol Membrane Z Disc Secretory Granule Lumen Extracellular Exosome Serine/threonine Protein Kinase Complex Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Binding Protein Binding Cadherin Binding Proline-rich Region Binding	Protein Binding Kinase Binding Protein Kinase Activator Activity Protein Serine/threonine Kinase Activator Activity
	Biological Process	Posttranscriptional Gene Silencing Negative Regulation Of Translation Insulin-like Growth Factor Receptor Signaling Pathway MRNA Destabilization	Cell Cycle Arrest Signal Transduction Positive Regulation Of Peptidyl-threonine Phosphorylation Response To Activity Peptidyl-serine Phosphorylation Activation Of Protein Kinase Activity Intracellular Signal Transduction Neutrophil Degranulation Cellular Hypotonic Response Positive Regulation Of Protein Serine/threonine Kinase Activity Response To Thyroid Hormone Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Potassium Ion Transmembrane Transport
Pathways			Energy dependent regulation of mTOR by LKB1-AMPK Neutrophil degranulation
Drugs
Diseases		Parkinson's disease (PD)
GWAS		Anxiety and stress-related disorders ( 31116379) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 32469254 29212778 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Schizophrenia ( 25056061 29483656 23974872)
Interacting Genes		8 interacting genes: APC CNOT9 GRB10 GRB14 GRB7 RBM12 SNRPB WBP11	12 interacting genes: CEP44 GOLGA2 IPO5 MCCD1 MED7 PRKAA1 RSL1D1 SHMT2 STK11 STK24 STRADA STRADB
Entrez ID		26058	51719
HPRD ID		11639	10091
Ensembl ID		ENSG00000204120	ENSG00000135932
Uniprot IDs		Q6Y7W6	A0A024R496 Q9Y376
PDB IDs		5NVL 5NVM	1UPK 1UPL 2WTK 3GNI 4FZA 4FZD 4FZF 4NZW 4O27
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?