AHCTF1 and NUP160

Data Source:
BioGRID (proximity labelling technology, two hybrid)

		AHCTF1	NUP160
Description		AT-hook containing transcription factor 1	nucleoporin 160
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Chromatin Nucleus Nuclear Pore Nucleoplasm Cytosol Nuclear Matrix Nuclear Pore Outer Ring Nuclear Membrane Extracellular Exosome	Kinetochore Nuclear Envelope Nuclear Pore Cytosol Nuclear Pore Outer Ring Host Cell
	Molecular Function	DNA Binding	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Cell Cycle Protein Transport Regulation Of Cytokinesis MRNA Transport Nuclear Pore Complex Assembly Cell Division	Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Viral Process Protein Sumoylation Viral Transcription Regulation Of Gene Silencing By MiRNA Nephron Development Intracellular Transport Of Virus Regulation Of Cellular Response To Heat
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation EML4 and NUDC in mitotic spindle formation	ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Body mass index ( 29273807) Brain morphology (MOSTest) ( 32665545) Fruit consumption ( 32066663) Global electrical heterogeneity phenotypes ( 29622589) Granulocyte percentage of myeloid white cells ( 27863252) Intraocular pressure ( 29617998 25173106 29235454) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Neuroticism ( 29255261) Neutrophil percentage of white cells ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Plateletcrit ( 27863252) Pulse pressure ( 30578418) Refractive error ( 32231278) Sleep duration (short sleep) ( 30846698) Systolic blood pressure ( 30578418)
Interacting Genes		1 interacting genes: NUP160	6 interacting genes: AHCTF1 DISC1 ESRRG EXOSC1 NUP37 SUMO2
Entrez ID		25909	23279
HPRD ID		09935	16254
Ensembl ID		ENSG00000153207	ENSG00000030066
Uniprot IDs		Q8WYP5	Q12769
PDB IDs			5A9Q
Enriched GO Terms of Interacting Partners?
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