DCAF13 and WARS1

Data Source:
BioGRID (two hybrid)

		DCAF13	WARS1
Description		DDB1 and CUL4 associated factor 13	tryptophanyl-tRNA synthetase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Centrosome Cytosol Cell Junction Small-subunit Processome Cul4-RING E3 Ubiquitin Ligase Complex	Nucleus Cytoplasm Cytosol Protein-containing Complex Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Estrogen Receptor Binding	Tryptophan-tRNA Ligase Activity Protein Binding ATP Binding Kinase Inhibitor Activity Protein Kinase Binding Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Protein Ubiquitination Post-translational Protein Modification	Angiogenesis Negative Regulation Of Protein Phosphorylation Translation TRNA Aminoacylation For Protein Translation Tryptophanyl-tRNA Aminoacylation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Regulation Of Protein ADP-ribosylation Positive Regulation Of Protein-containing Complex Assembly Regulation Of Angiogenesis
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Neddylation	Cytosolic tRNA aminoacylation
Drugs			Tryptophan Tryptophanyl-5'amp Tryptophanamide
Diseases
GWAS
Interacting Genes		3 interacting genes: PTEN TK1 WARS1	10 interacting genes: APP CDK2AP2 DCAF13 DNMT3B EEF1A1 LIG4 LINC01554 MDH2 TERF1 UBC
Entrez ID		25879	7453
HPRD ID		08528	01845
Ensembl ID		ENSG00000164934	ENSG00000140105
Uniprot IDs		A0A087WT20 Q9NV06	A0A024R6K8 P23381
PDB IDs			1O5T 1R6T 1R6U 1ULH 2AKE 2AZX 2DR2 2QUH 2QUI 2QUJ 2QUK 5UJI 5UJJ
Enriched GO Terms of Interacting Partners?
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