TNFAIP8 and EAPP

Data Source:
BioGRID (two hybrid)

		TNFAIP8	EAPP
Description		TNF alpha induced protein 8	E2F associated phosphoprotein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process	Protein Binding
	Biological Process	Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Pathways		PI Metabolism
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Apolipoprotein A1 levels ( 32203549) Asthma ( 31361310 31959851 32296059 31619474) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Heschl's gyrus morphology ( 25130324) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Multiple sclerosis ( 31604244) Plantar fascial disorders ( 29534260) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271) Triglyceride levels ( 32203549 32154731) Triglycerides ( 30275531) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 28552196 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412) White blood cell count ( 32888494)	Celiac disease ( 23936387) Insulin-related traits (multivariate analysis) ( 32002517) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: ATN1 EAF1 EAPP INO80E MED4 PLEKHF1 PLEKHF2 PRR13 SDCBP TIFA	5 interacting genes: AAR2 BYSL TNFAIP8 UBE3A UBQLN4
Entrez ID		25816	55837
HPRD ID		18204	12631
Ensembl ID		ENSG00000145779	ENSG00000129518
Uniprot IDs		B3KUI2 O95379	Q56P03
PDB IDs
Enriched GO Terms of Interacting Partners?
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