VAX2 and UFSP1

Data Source:
BioGRID (two hybrid)

		VAX2	UFSP1
Description		ventral anterior homeobox 2	UFM1 specific peptidase 1 (inactive)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Chromatin DNA Binding Sequence-specific Double-stranded DNA Binding	Molecular_function Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Ectoderm Development Axonogenesis Central Nervous System Development Visual Perception Dorsal/ventral Axis Specification Wnt Signaling Pathway Neuron Differentiation Forebrain Development Embryonic Eye Morphogenesis Retina Development In Camera-type Eye	Biological_process
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Atopic dermatitis ( 26482879) Corneal astigmatism ( 23322567) Gut microbiota (functional units) ( 27694959)	Bipolar disorder ( 31043756) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Nonunion in individuals with fractures ( 30680360) Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020) Resting heart rate ( 29769521 27798624 20639392)
Interacting Genes		3 interacting genes: PFDN5 POU6F2 UFSP1	42 interacting genes: C10orf55 CIDEB CIDEC COG6 CREB5 CSTF2 FAM222B FANCL FOXH1 FOXI1 GLYCTK GPSM3 HNF1B HOXC9 HSF4 INCA1 KRTAP15-1 LASP1 MSRB3 MYOZ3 PITX1 PITX2 POGZ POU6F2 PROP1 PRR22 RAPGEF3 RBPMS2 RUSC1 SMARCC1 SNRPC SPG21 TBX3 TCF7L2 TLX3 UBQLN2 VAC14 VAX2 VGLL3 VPS37C WWOX ZIC1
Entrez ID		25806	402682
HPRD ID		05051	18630
Ensembl ID		ENSG00000116035	ENSG00000176125
Uniprot IDs		F1T0K5 Q9UIW0	Q6NVU6
PDB IDs
Enriched GO Terms of Interacting Partners?
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