BAMBI and SOX30

Data Source:
HPRD (two hybrid)

		BAMBI	SOX30
Description		BMP and activin membrane bound inhibitor	SRY-box transcription factor 30
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Membrane	Chromatin Nucleus Cytoplasm Chromocenter
	Molecular Function	Frizzled Binding Type II Transforming Growth Factor Beta Receptor Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Beta-catenin Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Regulation Of Cell Shape Positive Regulation Of Epithelial To Mesenchymal Transition Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Protein Binding Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Canonical Wnt Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Spermatid Development Negative Regulation Of Wnt Signaling Pathway Response To Corticosteroid Positive Regulation Of Transcription By RNA Polymerase II Proacrosomal Vesicle Fusion
Pathways		Downregulation of TGF-beta receptor signaling
Drugs
Diseases
GWAS		Cataracts (operation) ( 31816047) Fasting glucose change (long-term) ( 31263163) Intraocular pressure ( 29617998) Metabolite levels ( 23823483) Percentage gas trapping ( 26030696) Preeclampsia ( 23551011)	Glycated hemoglobin levels ( 28898252) Triglyceride levels ( 31647587)
Interacting Genes		9 interacting genes: ACVR1 ACVR1B ACVRL1 BMPR1A BMPR1B NKG7 SELENOF SOX30 TGFBR1	18 interacting genes: AHCYL1 AURKA BAMBI BRCA1 CFAP206 CUL5 DCAF4 DDX56 FBXO38 FHL2 FLI1 GNAI3 GP2 KIFC3 NME1 NUDT3 PAXIP1 TRAF2
Entrez ID		25805	11063
HPRD ID		05117	09461
Ensembl ID		ENSG00000095739	ENSG00000039600
Uniprot IDs		Q13145	B4DXW7 O94993
PDB IDs			7JJK
Enriched GO Terms of Interacting Partners?
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