BCL6B and ZBTB7B

Data Source:
BioGRID (two hybrid)

		BCL6B	ZBTB7B
Description		BCL6B transcription repressor	zinc finger and BTB domain containing 7B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process Regulation Of Transcription By RNA Polymerase II Type 2 Immune Response Regulation Of Cell Population Proliferation Regulation Of Cell Differentiation Regulation Of Inflammatory Response	Negative Regulation Of Transcription By RNA Polymerase II NK T Cell Differentiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Ectoderm Development Lactation Positive Regulation Of Gene Expression Positive Regulation Of Histone Deacetylation Interleukin-17 Production Response To Insulin Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Negative Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of NK T Cell Proliferation Positive Regulation Of Brown Fat Cell Differentiation Positive Regulation Of Cold-induced Thermogenesis Adaptive Thermogenesis Negative Regulation Of T-helper 17 Cell Differentiation Positive Regulation Of SREBP Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Height ( 31562340) Platelet distribution width ( 32888494)	Adult body size ( 32376654) Basal cell carcinoma ( 31174203) Bipolar disorder ( 31043756) Birth weight ( 27680694) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29273807) Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hematocrit ( 32888494) Hemoglobin ( 32888494) Keratinocyte cancer (MTAG) ( 31174203) Multiple sclerosis ( 31604244) Prostate cancer ( 23535732) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		28 interacting genes: BAG4 BCL6 CALCOCO2 CARD10 CRBN FHL5 GOLGA2 GOLGA6L9 HDAC1 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 MDFI MID2 NOTCH2NLA PLSCR1 RBPMS SIN3A TRAF4 TSGA10 ZBTB7B	28 interacting genes: BCL6 BCL6B CCNL2 CRBN EP300 FAM90A1 GRAP2 GRB2 IMP4 KPNA2 MORF4L2 NCK2 NDN OSTF1 P4HA3 PIN1 RELA RPL9 SH3KBP1 SH3YL1 SORBS3 SYTL4 TRIP10 UBTFL1 ZBTB42 ZBTB5 ZNF277 ZSCAN5B
Entrez ID		255877	51043
HPRD ID		16414	09625
Ensembl ID		ENSG00000161940	ENSG00000160685
Uniprot IDs		A8KA13 Q8N143	O15156
PDB IDs
Enriched GO Terms of Interacting Partners?
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