RNF144B and PAN2

Data Source:
BioGRID (two hybrid)

		RNF144B	PAN2
Description		ring finger protein 144B	poly(A) specific ribonuclease subunit PAN2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytoplasm Cytosol Integral Component Of Membrane Mitochondrial Membrane	P-body Nucleus Cytosol PAN Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	3'-5'-exoribonuclease Activity Nucleic Acid Binding Poly(A)-specific Ribonuclease Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Metal Ion Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Apoptotic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Processing Proteolysis Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly Protein Phosphopantetheinylation RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Deadenylation of mRNA
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at voice drop ( 27182965) Caudal middle frontal gyrus volume ( 31530798) Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Chronotype ( 30696823) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Endometriosis ( 23472165) Facial morphology ( 31763980) General risk tolerance (MTAG) ( 30643258) Gut microbiota relative abundance (Dorea) ( 33208821) Pulse pressure ( 30224653) Thiopurine S-methyltransferase activity ( 27770449) Triglyceride levels ( 32203549)	Axial length ( 24144296) Height ( 25429064) Refractive error ( 32231278)
Interacting Genes		28 interacting genes: ANKS1A CDKN1A CHCHD2 CREB5 FOXH1 IL16 OTX1 PAN2 PAX5 PRKAB2 PROP1 PRR35 RIPPLY1 SGTA SGTB TRAF4 UBC UBE2I UBE2L3 UBE2L6 UBE2T UBE2U UBE2Z UBQLN1 USP15 USP2 VENTX ZIC1	7 interacting genes: DYNLL1 PABPC1 PAN3 RBCK1 RNF144B TNRC6A TRIM35
Entrez ID		255488	9924
HPRD ID		17126	15640
Ensembl ID		ENSG00000137393	ENSG00000135473
Uniprot IDs		Q7Z419	Q504Q3
PDB IDs
Enriched GO Terms of Interacting Partners?
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