GABPA and HCFC1

Data Source:
BioGRID (pull down)
HPRD (in vitro, two hybrid)

		GABPA	HCFC1
Description		GA binding protein transcription factor subunit alpha	host cell factor C1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Histone Acetyltransferase Complex Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex Cytoplasm Membrane Protein-containing Complex Histone Methyltransferase Complex Neuronal Cell Body Set1C/COMPASS Complex SAGA-type Complex MLL1 Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Activating Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Chromatin Binding Transcription Coactivator Activity Protein Binding Protein-macromolecule Adaptor Activity Activating Transcription Factor Binding Identical Protein Binding Cadherin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Formation Regulation Of Transcription By RNA Polymerase II Mitochondrion Organization Positive Regulation Of Gene Expression Cell Differentiation Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Dopamine	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of Transcription, DNA-templated Mitochondrion Organization Cell Cycle Positive Regulation Of Gene Expression Protein Deubiquitination Release From Viral Latency Regulation Of Protein-containing Complex Assembly Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein Stabilization
Pathways		Transcriptional activation of mitochondrial biogenesis	Transcriptional activation of mitochondrial biogenesis HATs acetylate histones UCH proteinases
Drugs
Diseases
GWAS		Gout (normal type) ( 32238385) Nicotine dependence symptom count ( 25555482)	Celiac disease ( 22057235) Rheumatoid arthritis ( 23143596) Rheumatoid arthritis (ACPA-positive) ( 23143596) Systemic lupus erythematosus ( 26502338)
Interacting Genes		13 interacting genes: APP ATF1 CREBBP EP300 GABPB1 GABPB2 HCFC1 MED1 PINX1 SP1 SP3 STK16 ZC2HC1B	33 interacting genes: ASF1B CLP1 CREB3 CREBZF E2F1 E2F3 E2F4 EGR2 FOXK2 GABPA GABPB1 HCFC1R1 HSPA1A JUN KMT2A MED25 NFE2L1 OGT PDCD2 POU2F1 PPARGC1A PPARGC1B PPP1CC PSIP1 SETD7 SIN3A SP1 SUMO2 TAF9 THAP11 THAP7 YY1 ZBTB17
Entrez ID		2551	3054
HPRD ID		11793	02061
Ensembl ID		ENSG00000154727	ENSG00000172534
Uniprot IDs		A8IE48 Q06546 Q8IYS3	A6NEM2 P51610
PDB IDs			4GO6 4N39 4N3A 4N3B 4N3C 5LWV 6MA1 6MA2 6MA3 6MA4 6MA5
Enriched GO Terms of Interacting Partners?
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