SLC37A4 and BIK

Data Source:
BioGRID (two hybrid)

		SLC37A4	BIK
Description		solute carrier family 37 member 4	BCL2 interacting killer
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Endomembrane System Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Glucose-6-phosphate Transmembrane Transporter Activity Glucose 6-phosphate:inorganic Phosphate Antiporter Activity	Protein Binding
	Biological Process	Glucose Metabolic Process Gluconeogenesis Carbohydrate Transport Glucose-6-phosphate Transport Phosphate Ion Transmembrane Transport	Apoptotic Process Male Gonad Development Apoptotic Mitochondrial Changes Positive Regulation Of Protein-containing Complex Assembly Regulation Of Apoptotic Process Positive Regulation Of Release Of Cytochrome C From Mitochondria
Pathways		Glycogen storage disease type Ib (SLC37A4) Gluconeogenesis
Drugs
Diseases		Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS			Prostate cancer ( 25939597 21743057) Prostate cancer (SNP x SNP interaction) ( 22219177)
Interacting Genes		4 interacting genes: BIK GLP1R GPR35 SHBG	95 interacting genes: ADGRE2 ADIPOQ AIG1 ALG8 ANKRD46 APOD APP ASB11 BCL2 BCL2A1 BCL2L1 BCL2L10 BCL2L2 BMP10 BNIP3 BRICD5 BTN2A2 C14orf180 C3orf52 C4orf3 CD53 CD72 CLDN19 CMTM5 CMTM7 CNIH1 CNIH3 CREB3 CRKL CTXN3 CXCL16 CYB561 CYB5B ELOVL4 ERGIC3 EXOC3L2 FAM209A FAM241B FAM3C FATE1 FCGR1A GPX8 GRM2 INSIG2 KCNN4 MARCHF5 MCL1 MS4A13 NAT8 NR2F2 NRM PBX3 PGAP2 PGRMC1 PLN PLP1 PLP2 PLPP4 REEP4 RUSF1 S100A1 SCAMP4 SEC22A SELENOK SERP1 SERP2 SLC35E3 SLC37A4 SLC39A7 SMIM1 SOCS3 STRIT1 STX8 TANK TMBIM1 TMEM107 TMEM11 TMEM14B TMEM14C TMEM199 TMEM222 TMEM229B TMEM243 TMEM254 TMEM60 TMEM80 TMEM86B TMEM97 TRARG1 TSPO2 UBE2D1 UBIAD1 VAMP3 VAMP5 ZFPL1
Entrez ID		2542	638
HPRD ID		04052	04547
Ensembl ID		ENSG00000137700	ENSG00000100290
Uniprot IDs		A0A024R3H9 A0A024R3L1 A8K0S7 B4DUH2 O43826	A0A024R4X6 Q13323
PDB IDs			2IPE
Enriched GO Terms of Interacting Partners?
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