G6PC1 and SNX13

Data Source:
BioGRID (two hybrid)

		G6PC1	SNX13
Description		glucose-6-phosphatase catalytic subunit 1	sorting nexin 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Early Endosome Early Endosome Membrane
	Molecular Function	Glucose-6-phosphatase Activity Protein Binding Phosphotransferase Activity, Alcohol Group As Acceptor Phosphate Ion Binding	Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding
	Biological Process	Glycogen Metabolic Process Glycogen Catabolic Process Gluconeogenesis Triglyceride Metabolic Process Steroid Metabolic Process Response To Carbohydrate Regulation Of Gene Expression Glucose-6-phosphate Transport Response To Food Cellular Response To Insulin Stimulus Multicellular Organism Growth Glucose Homeostasis Cholesterol Homeostasis Urate Metabolic Process Phosphorylated Carbohydrate Dephosphorylation Glucose 6-phosphate Metabolic Process Response To Resveratrol	Intracellular Protein Transport Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways		Glycogen storage disease type Ia (G6PC) Gluconeogenesis FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Drugs
Diseases		Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS			Adiponectin levels ( 31178129) Apolipoprotein A1 levels ( 32203549) Creatine kinase levels ( 29403010) Fibrinogen ( 23969696) Fibrinogen levels ( 28107422) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol ( 24097068 30275531) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) Heel bone mineral density ( 30598549) Lactate dehydrogenase levels ( 29403010) LDL cholesterol levels x long total sleep time interaction (1df test) ( 31719535) LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Metabolic syndrome ( 31589552) Neutrophil count ( 32888494) Parkinson's disease progression (composite) ( 33111402) Severe influenza A (H1N1) infection ( 26379185) Tea consumption ( 31046077) Triglyceride levels ( 32203549 32154731) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		4 interacting genes: CDH16 FOXO1 NSL1 SNX13	5 interacting genes: G6PC1 GNAS KLF15 NR1I3 TDP2
Entrez ID		2538	23161
HPRD ID		01983	09418
Ensembl ID		ENSG00000131482	ENSG00000071189
Uniprot IDs		P35575	A0A024R9Z9 Q86XC4 Q9Y5W8
PDB IDs
Enriched GO Terms of Interacting Partners?
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