FYN and PIK3R3

  • Data Source:
  • BioGRID (two hybrid)

FYN

PIK3R3

Description FYN proto-oncogene, Src family tyrosine kinase phosphoinositide-3-kinase regulatory subunit 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body mass index ( 26426971 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Brain morphology (min-P) ( 32665545)
  • Brain morphology (MOSTest) ( 32665545)
  • Breast cancer ( 29059683)
  • Cortical surface area (min-P) ( 32665545)
  • Cortical surface area (MOSTest) ( 32665545)
  • Cortical thickness (min-P) ( 32665545)
  • Cortical thickness (MOSTest) ( 32665545)
  • Diastolic blood pressure ( 30224653)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Estimated glomerular filtration rate ( 31152163)
  • Lymphocyte percentage of white cells ( 32888494)
  • Metabolite levels ( 23823483)
  • Neutrophil count ( 32888494)
  • Neutrophil percentage of white cells ( 32888494)
  • Red cell distribution width ( 32888494)
  • Sodium levels ( 29403010)
  • Subcortical volume (min-P) ( 32665545)
  • Subcortical volume (MOSTest) ( 32665545)
  • Sum neutrophil eosinophil counts ( 27863252)
  • White blood cell count ( 32888494 27863252)
Interacting Genes 198 interacting genes: ACP1 ADAM15 ADD2 ARHGAP32 ARHGAP33 ATXN1 BAG4 BCAR1 BCL3 BTK C7orf25 C8orf33 CASP3 CASP8 CAV1 CBL CBLB CBLC CD19 CD2 CD226 CD247 CD2AP CD36 CD44 CD48 CD5 CD55 CD79A CD79B CDH1 CDK1 CDK5 CLTC CMA1 CNN1 CNN3 CNTN1 CNTNAP1 CRK CSF1R CSF2RB CSK CTLA4 CTNNB1 CTNND2 DAG1 DLG4 DLGAP4 DOK1 DOK3 DOK4 DTX3 EFS ENO1 EPHA3 EPHA4 EPHA8 EPHB3 ERRFI1 EVL FAM90A1 FAS FASLG FCER2 FCGR2A FLOT1 FLOT2 FLT1 FNBP4 FYB1 GAB3 GP6 GRAP GRB10 GRB2 GRIN1 GRIN2A GRIN2B HNRNPK HRAS HSP90AA1 HTR6 IGHA1 IL1B IL2RB IL7R IRS1 ITCH ITGB4 ITK ITPR1 JAK2 JUP KDM1A KDR KHDRBS1 KIT LAT LCK LCP2 MAG MAP2 MAPT MCAM MED28 MEOX2 MS4A1 NCAM1 NEDD4 NEDD9 NMT1 NOS1AP NPHS1 NR3C1 NTRK2 PAG1 PAK2 PDE4D PDGFRB PECAM1 PIK3R1 PIK3R2 PIK3R3 PLAUR PLCG1 PLCG2 PLD2 PRKCD PRKCE PRKCH PRKCQ PRKCZ PRMT6 PRMT8 PTK2 PTK2B PTPN11 PTPN5 PTPRA PTPRC PTPRE PTPRF PTPRZ1 PXN RACK1 RAF1 RPL10 RPS6KA3 RPS6KB2 SDC3 SH2B2 SH2D1A SH3BP2 SHC1 SIT1 SKAP1 SKAP2 SLAMF1 SNCA SOCS1 SOS1 SPHK1 SPHK2 SPN STAT1 STAT3 SUV39H1 SYK TAMALIN TCAP THY1 TNF TNK2 TNNT1 TOM1L1 TRAF6 TRAT1 TRIM55 TRIM63 TRPC6 TRPV4 TUBA1B TUBA3C TUBA4A TXK TYK2 TYRO3 UHRF2 UNC119 VAV1 VAV2 WAS WASF1 WASF2 WBP11 YTHDC1 ZAP70 124 interacting genes: ABCB6 ABL2 AMBP ANKS1A ANTKMT AR ARID4B AUNIP AXL BLK BLZF1 BRK1 BTK C3orf36 C9orf24 CAMK1 CCDC14 CCDC196 CCDC33 CCDC89 CEP126 CEP19 CHRDL2 CLNK CRBN CRK DARS1 DCAF8 DISC1 DRAP1 DSN1 E2F6 EGFR ENKD1 ERBB2 ERBB3 ERBB4 ESR1 FAM166B FBN3 FER FGB FNDC8 FOXO1 FSD2 FYN GAB1 GC GRB2 HROB HSH2D IGF1R INSR IQUB IRS1 IRS2 ITGB3BP KARS1 KHDRBS1 KIAA0408 KIT KLC2 KLF15 KMT2B L3MBTL3 LAP3 LNX2 LUC7L2 MBIP MECOM MET MICAL1 MTF2 NAB2 NCK1 NEBL NEDD9 ORM1 PACRGL PBX4 PCDHB5 PDGFRB PELO PIK3CA PIK3CD PLAAT4 PLB1 PLEKHF2 PPARA PRKAR1B PSME1 PTK2 QARS1 RB1 RING1 RUSC1 SERF1A SERTAD2 SOCS6 SPATA32 SRC SSBP4 STAT3 STAT5B TASOR2 TEC TERF2 TNK2 TNNC2 TNNI1 TRIM54 TRMT2A TSPAN2 USP2 VBP1 VCP WRNIP1 YES1 YPEL3 ZBTB18 ZMAT1 ZNF281 ZNF451 ZNF620
Entrez ID 2534 8503
HPRD ID 00655 05831
Ensembl ID ENSG00000010810 ENSG00000117461
Uniprot IDs P06241 B4DXM8 Q68CY7 Q7Z3W2 Q8N381 Q92569
PDB IDs 1A0N 1AOT 1AOU 1AVZ 1AZG 1EFN 1FYN 1G83 1M27 1NYF 1NYG 1SHF 1ZBJ 2DQ7 2MQI 2MRJ 2MRK 3H0F 3H0H 3H0I 3UA6 3UA7 4D8D 4EIK 4U17 4U1P 4ZNX 5ZAU 6EDF 6IPY 6IPZ
Enriched GO Terms of Interacting Partners?
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