FUT3 and AKAP6

Data Source:
BioGRID (affinity chromatography technology)

		FUT3	AKAP6
Description		fucosyltransferase 3 (Lewis blood group)	A-kinase anchoring protein 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Membrane Integral Component Of Membrane Golgi Cisterna Membrane Extracellular Exosome	Nuclear Envelope Cytoplasm Caveola Junctional Sarcoplasmic Reticulum Membrane Intercalated Disc Sarcoplasmic Reticulum T-tubule Nuclear Membrane Calcium Channel Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Fucosyltransferase Activity 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase Activity 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase Activity Alpha-(1->3)-fucosyltransferase Activity	Protein Binding Adenylate Cyclase Binding Protein Kinase A Regulatory Subunit Binding Protein-membrane Adaptor Activity Ion Channel Binding Protein Kinase A Binding Molecular Adaptor Activity
	Biological Process	Protein Glycosylation Ceramide Metabolic Process Oligosaccharide Metabolic Process Oligosaccharide Biosynthetic Process Cell-cell Recognition Positive Regulation Of Cell-cell Adhesion Regulation Of Cell Migration Fucosylation Regulation Of Cell Population Proliferation Macromolecule Glycosylation	Action Potential Protein Targeting Regulation Of Protein Kinase A Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum CAMP-mediated Signaling Positive Regulation Of Cell Growth Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Membrane Repolarization Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Positive Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To CAMP Cellular Response To Cytokine Stimulus Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Delayed Rectifier Potassium Channel Activity
Pathways		Lewis blood group biosynthesis Reactions specific to the complex N-glycan synthesis pathway
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Elevated serum carcinoembryonic antigen levels ( 24941225) N-glycan levels ( 21908519 21203500) Serum cancer antigen 19.9 levels ( 31666285) Vitamin B12 levels ( 28334792)	Adult body size ( 32376654) Anorexia nervosa ( 21079607) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Asthma ( 29273806) Atrial fibrillation ( 30061737 29892015) Bipolar disorder ( 31043756) Body mass index ( 28892062 25673413 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Coffee consumption ( 31046077) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive function ( 25644384) Creatine kinase levels ( 29403010) Diisocyanate-induced asthma ( 25918132) Economic and political preferences (environmentalism) ( 22566634) Fasting blood insulin (BMI interaction) ( 22581228) General cognitive ability ( 29844566) Glioma ( 28346443) HDL cholesterol levels ( 32203549) Intelligence (MTAG) ( 29326435) Night sleep phenotypes ( 27126917) Non-glioblastoma glioma ( 28346443) Photic sneeze reflex ( 27182965) PR interval ( 32439900) Refractive error ( 32231278) Schizophrenia ( 28991256 30285260) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Type 2 diabetes ( 30297969)
Interacting Genes		5 interacting genes: C3orf52 FAM3B SEC22A SLC41A2 TRARG1	9 interacting genes: CALM1 CDC5L DISC1 DTNBP1 PDE4D PPP2CA PRKAR2A RYR1 RYR2
Entrez ID		2525	9472
HPRD ID		00196	05257
Ensembl ID		ENSG00000171124	ENSG00000151320
Uniprot IDs		A8K737 P21217	B2RP22 Q13023
PDB IDs
Enriched GO Terms of Interacting Partners?
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