GAST and CISD2

Data Source:
BioGRID (two hybrid)

		GAST	CISD2
Description		gastrin	CDGSH iron sulfur domain 2
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Protein-containing Complex Perinuclear Endoplasmic Reticulum
	Molecular Function	Hormone Activity Protein Binding	RNA Binding Protein Binding Protein Homodimerization Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Response To Food	Autophagy Of Mitochondrion Multicellular Organism Aging Regulation Of Autophagy
Pathways		G alpha (q) signalling events Gastrin-CREB signalling pathway via PKC and MAPK
Drugs		Oxetacaine
Diseases			Wolfram syndrome (WFS); DIDMOAD syndrome
GWAS			Asthma and attention deficit hyperactivity disorder ( 31619474) Estimated glomerular filtration rate ( 31152163) Primary biliary cholangitis ( 26394269) Schizophrenia ( 28991256) Type 2 diabetes ( 28869590)
Interacting Genes		24 interacting genes: AQP6 AQP9 ASPH BCL2L13 CISD2 CP CPE CREB3L1 CYB5R3 ERGIC3 FAM209A GOLM1 GPR152 KIR2DL3 KRT34 LHFPL2 MEP1B MMD MME MUC1 PDZK1IP1 PLP1 SLC10A1 TMEM52B	58 interacting genes: AIG1 APOL2 APP AQP10 BCL2L2 BET1 BMP10 BTN2A2 C14orf180 C2CD2L C4orf3 CDIPT CFHR5 CLDN10 CLN6 CYBC1 EHHADH EMD FAM241B GALNT15 GAST GPR37L1 HHATL IER3 KIR2DL3 LEPROTL1 LRP10 MAN2B2 MIP NAPB NRG4 NSG1 PGAP2 PLPP4 PLPPR2 PNKP POMGNT1 RTP2 RUSF1 SEC22A SERP2 SLC13A3 SLC35B4 SMIM1 SNORC SPP1 STX12 STX7 THSD7B TMEM187 TMEM243 TMEM43 TMEM86A TSPAN33 TTPA VAMP4 VKORC1L1 YIPF6
Entrez ID		2520	493856
HPRD ID		00671	17413
Ensembl ID		ENSG00000184502	ENSG00000145354
Uniprot IDs		A0A0E3VY36 P01350	Q8N5K1
PDB IDs		5WRJ	3FNV 4OO7 4OOA
Enriched GO Terms of Interacting Partners?
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