FUCA1 and MED10

Data Source:
BioGRID (two hybrid)

		FUCA1	MED10
Description		alpha-L-fucosidase 1	mediator complex subunit 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Lysosome Azurophil Granule Lumen Lysosomal Lumen Extracellular Exosome	Ubiquitin Ligase Complex Chromatin Nucleoplasm Mediator Complex
	Molecular Function	Alpha-L-fucosidase Activity Protein Binding	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Fucose Metabolic Process Glycosaminoglycan Catabolic Process Glycoside Catabolic Process Glycolipid Catabolic Process Neutrophil Degranulation	Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Neutrophil degranulation Reactions specific to the complex N-glycan synthesis pathway	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases		Fucosidosis
GWAS		Arterial stiffness index ( 31235810) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		7 interacting genes: APP BARD1 CIB1 MED10 PAXIP1 UBQLN2 VAV2	12 interacting genes: ABI2 ARHGDIG ESR1 ESR2 FUCA1 HNF4A KDM4B MOB4 NAP1L1 PEBP1 SYCE1L TRIM45
Entrez ID		2517	84246
HPRD ID		01974	14680
Ensembl ID		ENSG00000179163	ENSG00000133398
Uniprot IDs		B5MDC5 P04066	Q9BTT4
PDB IDs
Enriched GO Terms of Interacting Partners?
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