ATP6V1C2 and KRTAP12-2

Data Source:
BioGRID (two hybrid)

		ATP6V1C2	KRTAP12-2
Description		ATPase H+ transporting V1 subunit C2	keratin associated protein 12-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Cytosol Extracellular Exosome	Cytosol Keratin Filament
	Molecular Function	Identical Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding
	Biological Process	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Positive Regulation Of Wnt Signaling Pathway Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Keratinization
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Keratinization
Drugs		Tiludronic acid
Diseases
GWAS		Cardiac Troponin-T levels ( 23247143)
Interacting Genes		7 interacting genes: GOLGA2 KLHL24 KRTAP12-2 MEOX2 PAX6 REL SPANXN3	125 interacting genes: ADAM12 ARID5A ATN1 ATP6V1C2 AVPI1 BCL6B BEX2 CATSPER1 CBLL2 CBX2 CCNL1 CCNL2 CFP CHRD CNNM3 CYSRT1 DGCR6 DHRS1 EFEMP2 ETNK2 FAM27E3 FHL3 FOXD4 FOXD4L1 FOXD4L3 GDF15 GPANK1 GPRIN2 GREM1 HOXA1 HOXB9 HSFX1 HSFX2 HYPK INO80B IQUB KRT34 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP21-2 KRTAP26-1 KRTAP3-2 KRTAP4-2 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1A LCE1C LCE1F LCE2A LCE2B LCE4A LINC00671 MEOX2 MGAT5B MYOZ1 MYPOP NBPF19 NECTIN2 NOTCH2NLA NPDC1 NR1D2 ODF1 OTX1 PACSIN3 PATZ1 PCSK5 PDE9A PELO PHLDA1 PIH1D2 PLAC8 POLR1C POM121L8P POU4F2 RAD23A RBM39 RBPMS RBX1 RHOXF2 SEMA3B SLC12A4 SLC13A5 SLC15A2 SLC15A3 SPATA3 SPRED2 SPRY1 SRSF8 TCEA2 TEX37 TINAGL1 TLE5 TMEM179B TNS2 TRIM42 TRIP13 TSGA10IP TTPA VASN VENTX VGLL3 YIPF3 YY1 ZBTB9 ZDHHC1 ZIM2 ZNF100 ZNF408 ZNF497 ZNF581 ZNF587 ZNF624 ZNF688 ZNF696 ZNF764 ZNF785 ZNHIT1
Entrez ID		245973	353323
HPRD ID		16523	11198
Ensembl ID		ENSG00000143882	ENSG00000221864
Uniprot IDs		A0A0U1RR16 Q8NEY4	P59991
PDB IDs
Enriched GO Terms of Interacting Partners?
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