KIF4A and PRC1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down, two hybrid)

		KIF4A	PRC1
Description		kinesin family member 4A	protein regulator of cytokinesis 1
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GO Annotations	Cellular Component	Nucleoplasm Chromosome Cytoplasm Cytosol Spindle Microtubule Membrane Nuclear Matrix Midbody Axon Cytoplasm	Spindle Pole Nucleus Nucleoplasm Chromosome Cytoplasm Spindle Cytosol Spindle Microtubule Plasma Membrane Microtubule Cytoskeleton Midbody Intercellular Bridge Contractile Ring Mitotic Spindle Midzone
	Molecular Function	DNA Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Metal Ion Binding Iron-sulfur Cluster Binding	Protein Binding Microtubule Binding Kinesin Binding Protein Kinase Binding
	Biological Process	Mitotic Cytokinesis Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Organelle Organization Microtubule-based Movement Mitotic Spindle Organization Anterograde Axonal Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Mitotic Spindle Midzone Assembly	Mitotic Spindle Elongation Microtubule Cytoskeleton Organization Microtubule Bundle Formation Positive Regulation Of Cell Population Proliferation Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly Cell Division
Pathways		MHC class II antigen presentation Recycling pathway of L1 Recycling pathway of L1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins	RHO GTPases activate CIT
Drugs
Diseases
GWAS			Breast cancer ( 29059683 25038754) Mean platelet volume ( 32888494 27863252) Multisite chronic pain ( 31194737) Red cell distribution width ( 32888494) Type 2 diabetes ( 22885922 24509480 30054458 30297969 26818947 32499647 20581827 30718926 28869590)
Interacting Genes		6 interacting genes: APP DNMT3B HMG20B PRC1 SUMO2 TTF2	29 interacting genes: AKAP9 CASK CCDC85B CCNA2 CCNB1 CCNE1 CDK1 CDK2 CINP FXR2 KIF3B KIF4A KLC2 KLC4 KRT20 MAT2A NDEL1 PCM1 PKIA PLK1 RACGAP1 RBM10 RPA2 SF3B2 SLAIN1 SUMO2 TRIM37 USHBP1 YWHAE
Entrez ID		24137	9055
HPRD ID		06606	17899
Ensembl ID		ENSG00000090889	ENSG00000198901
Uniprot IDs		O95239 Q59HG1	A0A024RC67 O43663
PDB IDs		6OYL	3NRX 3NRY 4L3I 4L6Y 5KMG
Enriched GO Terms of Interacting Partners?
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