PPIL2 and BSG

Data Source:
HPRD (in vivo)

		PPIL2	BSG
Description		peptidylprolyl isomerase like 2	basigin (Ok blood group)
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Lumen Plasma Membrane	Golgi Membrane Photoreceptor Outer Segment Photoreceptor Inner Segment Acrosomal Membrane Mitochondrion Endosome Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Basolateral Plasma Membrane Axon Sarcolemma Melanosome Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Exosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Ubiquitin-ubiquitin Ligase Activity Ubiquitin Protein Ligase Activity	Virus Receptor Activity Protein Binding Mannose Binding Cadherin Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Protein Polyubiquitination Protein Peptidyl-prolyl Isomerization Protein Folding Leukocyte Migration Protein Localization To Plasma Membrane	Angiogenesis Pyruvate Metabolic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell Surface Receptor Signaling Pathway Axon Guidance Embryo Implantation Extracellular Matrix Disassembly Extracellular Matrix Organization Neutrophil Chemotaxis Odontogenesis Of Dentin-containing Tooth Response To Peptide Hormone Response To Mercury Ion Decidualization Viral Entry Into Host Cell Leukocyte Migration Response To CAMP Dendrite Self-avoidance Protein Localization To Plasma Membrane
Pathways		Basigin interactions	Degradation of the extracellular matrix Basigin interactions Integrin cell surface interactions Proton-coupled monocarboxylate transport Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) Pyruvate metabolism
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) ( 29310926) Type 1 diabetes in high risk HLA genotype individuals (time to event) ( 29310926)	Alzheimer's disease (late onset) ( 28714976)
Interacting Genes		8 interacting genes: APP BSG CALM1 CRNKL1 HSP90AA1 PRCC SNAI1 TRIM23	18 interacting genes: ADRB2 AQP6 CAV1 CCR4 CHRM3 CRBN F2RL1 HGS MMP1 PDLIM7 PPIA PPIL2 PPP2R1B SLC16A1 SLC16A13 SLC16A3 SLC2A4 UBC
Entrez ID		23759	682
HPRD ID		08472	00176
Ensembl ID		ENSG00000100023	ENSG00000172270
Uniprot IDs		A0A024R1C1 A8K0I0 Q13356	P35613 Q54A51
PDB IDs		1ZKC	3B5H 3I84 3I85 3QQN 3QR2 4U0Q 5X0T 5XF0
Enriched GO Terms of Interacting Partners?
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