PLD3 and CNIH3

Data Source:
BioGRID (two hybrid)

		PLD3	CNIH3
Description		phospholipase D family member 3	cornichon family AMPA receptor auxiliary protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Endosome Membrane Late Endosome Membrane Lysosomal Lumen Extracellular Exosome	Golgi Membrane Endoplasmic Reticulum Membrane ER To Golgi Transport Vesicle Membrane Dendrite AMPA Glutamate Receptor Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Dendritic Shaft Synapse Postsynaptic Membrane
	Molecular Function	Phospholipase D Activity Protein Binding Single-stranded DNA 5'-3' Exodeoxyribonuclease Activity	Protein Binding Channel Regulator Activity
	Biological Process	Immune System Process DNA Metabolic Process Inflammatory Response Myotube Differentiation Nucleic Acid Phosphodiester Bond Hydrolysis Regulation Of Cytokine Production Involved In Inflammatory Response	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Synaptic Transmission, Glutamatergic Regulation Of Membrane Potential COPII Vesicle Coating Regulation Of AMPA Receptor Activity
Pathways		Synthesis of PG Role of phospholipids in phagocytosis	COPII-mediated vesicle transport Cargo concentration in the ER
Drugs
Diseases
GWAS		Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)	Cancer ( 29299148) Gut microbiota relative abundance (Streptococcus) ( 33208821) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Opioid dependence ( 26239289) White blood cell count ( 32888494)
Interacting Genes		12 interacting genes: ANXA7 BCL2L1 CNIH3 GPR35 HGS NFKB1 OPRM1 SMCO4 SOX4 SPP1 STK11 TK1	28 interacting genes: AQP6 BIK CD79A CEACAM3 CLDN20 ERGIC3 FAM210B FNDC9 GPX8 KCNN4 LEUTX LMNA LRRC25 NEMP1 ODF4 PLD3 SLC16A2 SMIM3 SORT1 STOM SUSD3 TMEM14B TMEM237 TMEM31 TMEM52B TMEM80 TMPRSS2 VSIR
Entrez ID		23646	149111
HPRD ID		07148	08799
Ensembl ID		ENSG00000105223	ENSG00000143786
Uniprot IDs		A0A024R0Q4 Q8IV08	Q8TBE1
PDB IDs
Enriched GO Terms of Interacting Partners?
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