LDOC1 and SUDS3

Data Source:
BioGRID (two hybrid)

		LDOC1	SUDS3
Description		LDOC1 regulator of NFKB signaling	SDS3 homolog, SIN3A corepressor complex component
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleus Nucleoplasm Cytosol Sin3 Complex Nuclear Body Sin3-type Complex
	Molecular Function	Protein Binding	Histone Deacetylase Activity Protein Binding Enzyme Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Protein Deubiquitination Substantia Nigra Development Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated
Pathways			HDACs deacetylate histones NoRC negatively regulates rRNA expression Ub-specific processing proteases Potential therapeutics for SARS
Drugs
Diseases
GWAS			Glucose homeostasis traits ( 25524916) Hemostatic factors and hematological phenotypes ( 22443383) Hippocampal sclerosis ( 25188341) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Morphine dose requirement in tonsillectomy and adenoidectomy surgery ( 24909733) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576)
Interacting Genes		107 interacting genes: AATF ABLIM1 AEBP2 AP1M1 AQP1 ATF4 ATP6V1G1 BARD1 BEX2 BYSL C1orf109 CCDC33 CCDC85B CDC5L CEBPE CFAP53 CTNNBL1 DPF2 DPPA4 ENKD1 FAM107A FAM110A FAM161A FAM193B FAM50B FAM90A1 FCHSD2 FOSL1 FXR2 GADD45GIP1 GNL3L GPANK1 HAUS1 HDAC4 HGS HOXB5 HOXC8 IKZF3 IKZF5 INPP1 IQCB1 JRK KRT15 KRT18 LATS1 LENG1 LMO2 LNX1 MBD3 MEAF6 MFAP1 MSGN1 MYC MZF1 NOD2 NRIP1 NXF1 PEG10 PLEKHF2 POLL PPP1R18 PRPF18 PRPF31 PSMA1 PSMF1 RAB29 RALBP1 RASSF10 RIBC1 RNF6 RPP25 SCNM1 SDCBP SETD5 SH2D4A SMARCB1 SMARCD1 SUDS3 TASOR2 TBC1D7 TCEANC TEAD4 THAP7 TLE5 TMSB4XP1 TNNT1 TSGA10IP TSNAX TTC23 UBTFL1 UTP14A WDR25 WT1 ZBTB16 ZBTB24 ZFP1 ZGPAT ZNF124 ZNF250 ZNF408 ZNF564 ZNF587 ZNF629 ZNF648 ZNF688 ZNF774 ZNF835	7 interacting genes: BRMS1 CSNK2A1 GOLGA2 HDAC1 LDOC1 PTEN SRPK1
Entrez ID		23641	64426
HPRD ID		02322	12196
Ensembl ID		ENSG00000182195	ENSG00000111707
Uniprot IDs		O95751	Q9H7L9
PDB IDs
Enriched GO Terms of Interacting Partners?
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