ARL2BP and ARL3

Data Source:
HPRD (two hybrid, in vitro)

		ARL2BP	ARL3
Description		ADP ribosylation factor like GTPase 2 binding protein	ADP ribosylation factor like GTPase 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrial Intermembrane Space Mitochondrial Matrix Centrosome Spindle Cytosol Cilium Midbody	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Spindle Microtubule Cytoplasmic Microtubule Cilium Microtubule Cytoskeleton Midbody Photoreceptor Connecting Cilium Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity Protein Binding GTPase Regulator Activity	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding GDP Binding GTPase Activating Protein Binding
	Biological Process	Signal Transduction Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Transcription, DNA-templated Regulation Of Catalytic Activity Regulation Of Insulin Secretion Maintenance Of Protein Location In Nucleus	Mitotic Cytokinesis Kidney Development Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Smoothened Signaling Pathway Small GTPase Mediated Signal Transduction Intraciliary Transport Photoreceptor Cell Development Cilium Assembly Protein Localization To Cilium Protein Localization To Ciliary Membrane
Pathways		Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	Trafficking of myristoylated proteins to the cilium
Drugs			2-(N-morpholino)ethanesulfonic acid Guanosine-5'-Diphosphate
Diseases
GWAS		Mean corpuscular hemoglobin concentration ( 29403010)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 30487518) Mean arterial pressure ( 30487518) Mean arterial pressure (long-term average) ( 28348047) Prostate cancer ( 23535732) Pulse pressure ( 30487518) Refractive error ( 32231278) Schizophrenia ( 28991256 25056061 27922604) Systolic blood pressure ( 30487518) Systolic blood pressure (long-term average) ( 28348047) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: ARL2 ARL3 CAMK2D CFAP20 MPP3 RAC1	11 interacting genes: ARL2BP GOLGA4 LRIF1 PDE6D RP2 TBL1X TLE1 TP53 TUBA1A UBR1 UNC119
Entrez ID		23568	403
HPRD ID		09808	05260
Ensembl ID		ENSG00000102931	ENSG00000138175
Uniprot IDs		A0A024R6U9 Q9Y2Y0	P36405
PDB IDs		2K9A 3DOE 3DOF
Enriched GO Terms of Interacting Partners?
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