LPAR3 and CYBRD1

Data Source:
BioGRID (two hybrid)

		LPAR3	CYBRD1
Description		lysophosphatidic acid receptor 3	cytochrome b reductase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Axon Synapse	Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Brush Border Membrane Extracellular Exosome
	Molecular Function	G-protein Alpha-subunit Binding G Protein-coupled Receptor Activity Protein Binding Phospholipid Binding Lipid Binding Lysophosphatidic Acid Receptor Activity	Ferric-chelate Reductase Activity Protein Binding Oxidoreductase Activity Metal Ion Binding
	Biological Process	Activation Of MAPK Activity G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemical Synaptic Transmission Regulation Of Metabolic Process Bleb Assembly Positive Regulation Of Collateral Sprouting Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Positive Regulation Of Calcium Ion Transport	Cellular Iron Ion Homeostasis Response To Iron Ion
Pathways		G alpha (q) signalling events G alpha (i) signalling events Lysosphingolipid and LPA receptors	Iron uptake and transport
Drugs
Diseases
GWAS		Cerebrospinal fluid t-tau:AB1-42 ratio ( 28641921) Dental caries ( 23064961) Glucose homeostasis traits ( 25524916) Heel bone mineral density ( 30598549) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)	Body fat distribution (arm fat ratio) ( 30664634) Heel bone mineral density ( 30598549) Pulse pressure ( 30224653)
Interacting Genes		58 interacting genes: APP AQP6 ARL13B ASZ1 BCL2L13 C16orf54 CD53 CD74 CD79A CLDN2 CLDN7 CLDN9 CLEC12B CPLX4 CREB3L1 CYB561 CYBRD1 EDA ERGIC3 FAM209A FAM210B FFAR2 FNDC9 GJB5 GNAI2 GORAB GPX8 JAGN1 KCNC1 KCNJ6 LEPROTL1 LHFPL5 LIME1 LMNA MFF MGST3 MRM1 MS4A4A NDUFAF2 OPRM1 PGRMC2 RELL2 RETREG3 SCN3B SGMS2 SHISAL1 SLC10A6 SLC16A2 SLC35C2 TFEC THAP4 TMEM14B TMEM237 TMEM31 TMEM41A TMEM52B TMEM70 TMEM79	20 interacting genes: CREB3 FKBP8 GIMAP5 GOSR2 HMOX1 LMNA LPAR3 NEDD4L PLP2 RABAC1 SEC22A SERP1 SERP2 STX4 STX7 TMEM120A TMEM65 VAPA VAPB ZFPL1
Entrez ID		23566	79901
HPRD ID		05486	05764
Ensembl ID		ENSG00000171517	ENSG00000071967
Uniprot IDs		Q9UBY5	Q53TN4
PDB IDs			5ZLE 5ZLG
Enriched GO Terms of Interacting Partners?
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