DDAH2 and DNAJB11

Data Source:
BioGRID (two hybrid)

		DDAH2	DNAJB11
Description		dimethylarginine dimethylaminohydrolase 2	DnaJ heat shock protein family (Hsp40) member B11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Chaperone Complex
	Molecular Function	Catalytic Activity Protein Binding Dimethylargininase Activity Amino Acid Binding	Protein Binding Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Citrulline Metabolic Process Arginine Metabolic Process Arginine Catabolic Process Nitric Oxide Biosynthetic Process Nitric Oxide Mediated Signal Transduction Negative Regulation Of Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric-oxide Synthase Activity	Protein Folding Positive Regulation Of ATPase Activity IRE1-mediated Unfolded Protein Response Protein Maturation
Pathways		eNOS activation	XBP1(S) activates chaperone genes
Drugs		Citrulline
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)
Interacting Genes		27 interacting genes: ACTN3 ANXA7 ATP1B1 CDC73 CDK4 CDKN1A DNAJB11 FANCL GADD45G IGFN1 MAP3K20 MKNK1 NOXA1 PIN1 PRKAB2 RAP1B RCC1 RPS6KA1 RPS6KA5 SMN1 STK3 TAF1D TK1 TNFSF11 TRIP13 TSC22D1 VAC14	24 interacting genes: ANKZF1 APOBEC1 BAG6 CEP70 COL6A1 CRMP1 DDAH2 DNAJC13 DRAP1 EIF3D EZH2 FAF1 GRB2 HSPA1A HTN3 PAXIP1 PTN SIMC1 SNX5 SPRED1 SUMO4 UBQLN4 UBR1 ZZZ3
Entrez ID		23564	51726
HPRD ID		09204	07485
Ensembl ID		ENSG00000213722	ENSG00000090520
Uniprot IDs		O95865 V9HW53	Q9UBS4
PDB IDs
Enriched GO Terms of Interacting Partners?
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