TNPO3 and ICA1L

Data Source:
BioGRID (two hybrid)

		TNPO3	ICA1L
Description		transportin 3	islet cell autoantigen 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Annulate Lamellae Cytoplasm Intracellular Membrane-bounded Organelle	Golgi Apparatus
	Molecular Function	Protein Binding Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity	Protein Binding Protein Domain Specific Binding
	Biological Process	Protein Import Into Nucleus	Regulation Of Transport
Pathways
Drugs
Diseases
GWAS		Diffuse cutaneous systemic sclerosis ( 29293537) Limited cutaneous systemic scleroderma ( 29293537) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary biliary cholangitis ( 20639880) Primary biliary cirrhosis ( 22961000) SjÃ¶gren's syndrome ( 24097067) Systemic lupus erythematosus ( 18204446 24871463 26606652 23053960 26502338 18204098 28714469) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic lupus erythematosus or rheumatoid arthritis ( 27193031) Systemic sclerosis ( 21750679 31672989 30247649 29293537) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic sclerosis (anti-topoisomerase-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Ulcerative colitis ( 23128233 21297633)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Heel bone mineral density ( 28869591) Ischemic stroke (small-vessel) ( 29531354) Mean platelet volume ( 32888494) Microalbuminuria ( 31511532) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Platelet count ( 32888494) Spontaneous coronary artery dissection ( 32887874) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532) White matter hyperintensities ( 32358547) White matter integrity (fractional anisotropy) ( 32358547)
Interacting Genes		19 interacting genes: BLMH CAMK2B CAMK2D CAMK2G CHMP3 CLPP ECI2 GCH1 ICA1L KRT75 KRTAP10-8 MEOX2 NME1 PPP1R1C SMURF2 SRSF1 SSX2 SSX2B TRA2B	9 interacting genes: DPY30 GCC1 HGS KIFC3 KRT27 LMO2 MTDH RCOR3 TNPO3
Entrez ID		23534	130026
HPRD ID		18209	12447
Ensembl ID		ENSG00000064419	ENSG00000163596
Uniprot IDs		A0A024R794 B3KMX1 Q9Y5L0	A0A024R3W3 Q8NDH6 Q96Q33
PDB IDs		4C0O 4C0P 4C0Q 4OL0 6GX9
Enriched GO Terms of Interacting Partners?
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