ETHE1 and ATP6V1H

Data Source:
HPRD (two hybrid)

		ETHE1	ATP6V1H
Description		ETHE1 persulfide dioxygenase	ATPase H+ transporting V1 subunit H
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix	Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Iron Ion Binding Protein Binding Hydrolase Activity, Acting On Ester Bonds Identical Protein Binding Sulfur Dioxygenase Activity	Protein Binding ATPase Activity Enzyme Regulator Activity Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Glutathione Metabolic Process Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase Hydrogen Sulfide Metabolic Process	Endocytosis Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Regulation Of Defense Response To Virus By Virus Regulation Of Catalytic Activity Phagosome Acidification Proton Transmembrane Transport
Pathways		Sulfide oxidation to sulfate	ROS and RNS production in phagocytes Nef Mediated CD4 Down-regulation Nef Mediated CD8 Down-regulation Insulin receptor recycling Transferrin endocytosis and recycling Blockage of phagosome acidification Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS			Bipolar disorder with mood-incongruent psychosis ( 23092984) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)
Interacting Genes		9 interacting genes: APP ATG9A ATP6V1H GORASP2 IGSF21 KRTAP19-2 LRIF1 RELA TXN2	10 interacting genes: ATP6V1E1 CDKN2B ETHE1 FLACC1 PPP1R12C SNPH SOX9 SPATA2 TANK TRIM14
Entrez ID		23474	51606
HPRD ID		09764	10591
Ensembl ID		ENSG00000105755	ENSG00000047249
Uniprot IDs		A0A0S2Z580 A0A0S2Z5B3 A0A0S2Z5N8 B2RCZ7 O95571	A0A024R7U9 A0A024R7X3 B3KUZ7 Q9UI12
PDB IDs		4CHL
Enriched GO Terms of Interacting Partners?
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