ZDHHC17 and ADD1

Data Source:
BioGRID (two hybrid)

		ZDHHC17	ADD1
Description		zinc finger DHHC-type palmitoyltransferase 17	adducin 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane Aggresome Cytoplasmic Vesicle Membrane Golgi-associated Vesicle Membrane Presynaptic Membrane Cell Projection Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion F-actin Capping Protein Complex Postsynaptic Density Nuclear Body
	Molecular Function	Signaling Receptor Binding Protein Binding Magnesium Ion Transmembrane Transporter Activity Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity Identical Protein Binding	RNA Binding Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Calmodulin Binding Transcription Factor Binding Spectrin Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Actin Filament Binding
	Biological Process	Axonogenesis Protein Phosphopantetheinylation Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Lipoprotein Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of ERK1 And ERK2 Cascade Magnesium Ion Transmembrane Transport	Cell Morphogenesis In Utero Embryonic Development Cell Volume Homeostasis Hemoglobin Metabolic Process Actin Cytoskeleton Organization Erythrocyte Differentiation Positive Regulation Of Protein Binding Multicellular Organism Growth IRE1-mediated Unfolded Protein Response Homeostasis Of Number Of Cells Within A Tissue Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Transmembrane Transport Cellular Response To Calcium Ion Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Adherens Junction Organization
Pathways			Caspase-mediated cleavage of cytoskeletal proteins XBP1(S) activates chaperone genes Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Mean arterial pressure x educational attainment (some college) interaction (2df) ( 32372009) Metabolite levels ( 23823483) Visceral fat ( 30942860)	Coffee consumption (cups per day) ( 31837886) Household income ( 31844048) Household income (MTAG) ( 31844048) Huntington's disease progression ( 28642124) Monocyte percentage of white cells ( 32888494)
Interacting Genes		192 interacting genes: - ABCG4 ACTR1B ADD1 AHDC1 AIDA AK3 ALKBH3 ANKRD50 ANXA11 APBB1IP ARFGAP3 ASF1A ASIC4 BCAS3 BEX2 BTF3 C1orf216 C20orf141 CBS CCDC120 CCDC7 CCNE2 CDSN CENPBD1P1 CHMP1A CIB1 CLRN3 CNDP2 CNKSR1 COG3 CSTA CTCFL CTHRC1 DALRD3 DELE1 DIXDC1 DLG4 DLK1 DR1 DTX3 E2F8 EDRF1 EEF1G ERCC6L EVL EXOSC9 EYA3 FAM207A FAM9A FBH1 FOXD4L6 FTL FUT2 FUT9 GABPB1 GABPB2 GATA1 GOLPH3L GPR135 GRB10 GUSBP3 H2AP H2BC9 H3C10 HBG1 HECTD3 HLA-A HLA-DRB1 HMBS HOXA3 HS1BP3 HTT IFT20 IFT57 INPP5D JMJD7-PLA2G4B KHDC4 KIAA0408 KNSTRN KRAS KRT17 KRT8P12 KRTAP11-1 KRTAP9-2 LCA5L LGALS9C LIN28A LMAN2L LNCRI LRRC45 LY6G6C MANF MAP3K19 MIIP MLH3 MRFAP1 MRFAP1L1 MSANTD3 MSRB2 MYBPHL MYOZ2 NCBP1 NEBL NFATC2IP NFYC NIFK NPFF ODF2 OFCC1 OTUD7B OTX2 PABIR3 PBRM1 PDZK1IP1 PHF5A PLEKHB1 PPP1R21 PPTC7 PRMT5 PTMA QRICH1 RAB39B RAD51 RANGRF RAP1B RBM5 RCAN3 RIC8A RNF20 RNF38 RSBN1L RUBCNL SCNM1 SEMA4G SF3A3 SHOX2 SKA3 SLC1A3 SLC25A31 SLC9A9 SMARCB1 SNAP25 SOX14 SP2 SPRED2 SPRY3 SPRY4 SREBF2 SRSF4 STK25 STN1 SUMF2 SYT1 TEAD1 THAP7 TIGD1 TMC6 TMCC1 TMEM115 TMEM186 TMTC1 TNFAIP1 TNFSF10 TOX TPGS2 TTC23 TTLL7 TUT7 TXNDC12 TXNDC15 UBAC1 UBE2K USP18 USP32 VN1R10P VSX2 WAC WDR20 YIF1A YTHDF3 ZCCHC17 ZFC3H1 ZFP2 ZFP36 ZFYVE19 ZNF333 ZNF341 ZNF597 ZNF624 ZNF667-AS1 ZSCAN9	24 interacting genes: ADD2 ATP1A1 C1orf109 CALM1 CASP3 CSNK2B GEMIN7 HMG20A HSF2BP HSPH1 ID2 ID3 KLHL42 MAP1LC3B PRKACA PRKCA PRKCD RFX1 ROCK1 SMARCC1 SPTA1 SPTB TK1 ZDHHC17
Entrez ID		23390	118
HPRD ID		09697	00036
Ensembl ID		ENSG00000186908	ENSG00000087274
Uniprot IDs		Q8IUH5	P35611
PDB IDs		3EU9 5W7I 5W7J
Enriched GO Terms of Interacting Partners?
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